Genetic Epidemiology: Methods and Applications - Couverture souple

Livre 17 sur 19: Modular Texts Series

Austin, Melissa A

 
9781780641812: Genetic Epidemiology: Methods and Applications
Couverture souple
ISBN 10 : 1780641818 ISBN 13 : 9781780641812
Editeur : CABI Publishing, 2013

Synopsis

Genetic epidemiology plays a key role in discovering genetic factors influencing health and disease, and in understanding how genes and environmental risk factors interact. There is growing interest in this field within public health, with the goal of translating the results into promoting health and preventing disease in both families and populations. This textbook provides graduate students with a working knowledge of genetic epidemiology research methods. Following an overview of the field, the book reviews key genetic concepts, provides an update on relevant genomic technology, including genome-wide chips and DNA sequencing, and describes methods for assessing the magnitude of genetic influences on diseases and risk factors. The book focuses on research study designs for discovering disease susceptibility genes, including family-based linkage analysis, candidate gene and genome-side association studies, assessing gene-environment interactions and epistasis, studies of Non-Mendelian inheritance, and statistical analyses of data from these studies. Specific applications of each research method are illustrated using a variety of diseases and risk factors relevant to public health, and useful web-based genetic analysis software, human reference panels, and repositories, that can greatly facilitate this work, are described. Concluding with a review of ethical issues and a framework for translating human genomics research to clinical practice and public health benefit, this textbook is an essential new resource for graduate students in epidemiology and public health genetics.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

À propos de l?auteur

Melissa A. Austin teaches at the University of Washington.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
CABI Publishing
Date d'édition
2013
Langue
anglais
ISBN 10 
1780641818
ISBN 13 
9781780641812
Reliure
Broché
Nombre de pages
216
Coordonnées du fabricant
non disponible
Personne responsable
non disponible