Current & Emerging Options for Hereditary Angioedema Management - Couverture souple

 
9781780841106: Current & Emerging Options for Hereditary Angioedema Management

Synopsis

Hereditary angioedema is a rare but severely disabling and life-threatening disease with an estimated prevalence in the general population of 1:50,000. However, the cardinal symptom - recurrent cutaneous swellings - can develop in many common conditions such as allergic reaction to food and drugs. Although targeted therapies have been available for the past three decades in Europe, they had been absent from the USA. This has changed significantly over the past 3 years with the conclusion from several Phase II and III trials. Many new therapeutic options are now available that directly target the C1-esterase inhibitor deficiency and subsequent downstream bradykinin and kallikrein release thought to be responsible for the majority of cases of the disease. The availability of these safe and efficacious drugs has changed the treatment paradigm for hereditary angioedema. This book reviews in details the therapeutic options that are available for hereditary angioedema, and provides physicians with the necessary knowledge to give their patients the appropriate treatments.

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Présentation de l'éditeur

Hereditary angioedema is a rare but severely disabling and life-threatening disease with an estimated prevalence in the general population of 1:50,000. However, the cardinal symptom - recurrent cutaneous swellings - can develop in many common conditions such as allergic reaction to food and drugs. Although targeted therapies have been available for the past three decades in Europe, they had been absent from the USA. This has changed significantly over the past 3 years with the conclusion from several Phase II and III trials. Many new therapeutic options are now available that directly target the C1-esterase inhibitor deficiency and subsequent downstream bradykinin and kallikrein release thought to be responsible for the majority of cases of the disease. The availability of these safe and efficacious drugs has changed the treatment paradigm for hereditary angioedema. This book reviews in details the therapeutic options that are available for hereditary angioedema, and provides physicians with the necessary knowledge to give their patients the appropriate treatments.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.