Dynemicin A, Uncialamycin and Analogues - Couverture rigide

Best, Daniel

9781785481505: Dynemicin A, Uncialamycin and Analogues

Couverture rigide

ISBN 10 : 1785481509 ISBN 13 : 9781785481505

Editeur : ISTE Press Ltd - Elsevier Inc, 2016

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Enediynes are natural products with highly active cytotoxicity and antibacterial activity, and thus have significant potential in the development of anti-cancer treatments. However, they are not readily available and can degrade rapidly during isolation; one solution is to produce them using total synthesis. Dynemicin A and uncialamycin are two such enediynes, with similar structures, for which total synthesis has been achieved. This book presents the isolation and preparation of these two compounds and their analogues through various synthesis strategies. Details of the structural elements essential to their anti-cancer activity are presented, with the objective of explaining and optimizing their biological activities and potential development as drugs.

Les informations fournies dans la section � Synopsis � peuvent faire r�f�rence � une autre �dition de ce titre.

� propos de l?auteur

Daniel Best is a postdoctoral researcher at the University of Rennes 1 in France. He is currently developing the synthesis of uncialamycin analogues.

Les informations fournies dans la section � A propos du livre � peuvent faire r�f�rence � une autre �dition de ce titre.

�diteur: ISTE Press Ltd - Elsevier Inc
Date d'�dition: 2016
Langue: anglais
ISBN 10: 1785481509
ISBN 13: 9781785481505
Reliure: Reli�
Nombre de pages: 144
Coordonn�es du fabricant: non disponible
Personne responsable: Barbara Criscuolo
b.criscuolo@lswr.it

Via Spadolini, 7
Milano
20141
Italie

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Dynemicin A, Uncialamycin and Analogues

Daniel Best, Mickael Jean, Pierre Van De Weghe

Edit� par ISTEPELS 2016-06-01, 2016

ISBN 10 : 1785481509 ISBN 13 : 9781785481505

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Dynemicin A, Uncialamycin and Analogues

Daniel Best

Edit� par Elsevier Science & Technology, ISTE Press - Elsevier, 2016

ISBN 10 : 1785481509 ISBN 13 : 9781785481505

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Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Enediynes are natural products with highly active cytotoxicity and antibacterial activity, and thus have significant potential in the development of anti-cancer treatments. However, they are not readily available and can degrade rapidly during isolation; one solution is to produce them using total synthesis.Dynemicin A and uncialamycin are two such enediynes, with similar structures, for which total synthesis has been achieved. This book presents the isolation and preparation of these two compounds and their analogues through various synthesis strategies. Details of the structural elements essential to their anti-cancer activity are presented, with the objective of explaining and optimizing their biological activities and potential development as drugs. Englisch. N� de r�f. du vendeur 9781785481505

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Dynemicin A, Uncialamycin and Analogues

Best, Daniel/ Jean, Mickael/ Weghe, Pierre Van De

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ISBN 10 : 1785481509 ISBN 13 : 9781785481505

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Hardcover. Etat : Brand New. 1st edition. 144 pages. 9.00x6.25x0.75 inches. In Stock. N� de r�f. du vendeur __1785481509

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Dynemicin A, Uncialamycin and Analogues

Best, Daniel; Jean, Mickael; Weghe, Pierre Van De

Edit� par ISTE Press - Elsevier, 2016

ISBN 10 : 1785481509 ISBN 13 : 9781785481505

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Dynemicin A, Uncialamycin and Analogues

Daniel Best

Edit� par Elsevier Science & Technology, ISTE Press - Elsevier, 2016

ISBN 10 : 1785481509 ISBN 13 : 9781785481505

Neuf Couverture rigide

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Buch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Enediynes are natural products with highly active cytotoxicity and antibacterial activity, and thus have significant potential in the development of anti-cancer treatments. However, they are not readily available and can degrade rapidly during isolation; one solution is to produce them using total synthesis.Dynemicin A and uncialamycin are two such enediynes, with similar structures, for which total synthesis has been achieved. This book presents the isolation and preparation of these two compounds and their analogues through various synthesis strategies. Details of the structural elements essential to their anti-cancer activity are presented, with the objective of explaining and optimizing their biological activities and potential development as drugs. N� de r�f. du vendeur 9781785481505

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