Resolving The Cholesterol Controversy: The Scientists Who Proved The Lipid Hypothesis Of Causation Of Atherosclerosis And Coronary Heart Disease - Couverture souple

Thompson, Gilbert R

 
9781800615878: Resolving The Cholesterol Controversy: The Scientists Who Proved The Lipid Hypothesis Of Causation Of Atherosclerosis And Coronary Heart Disease
Couverture souple
ISBN 10 : 1800615876 ISBN 13 : 9781800615878
Editeur : WSPC (EUROPE), 2023

Synopsis

Resolving the Cholesterol Controversy recounts the science and scientific personalities behind the chain of discoveries upon which the lipid hypothesis of atherosclerosis was built. The narrative covers a period of just under 100 years, starting with Anitschkow's experiments with cholesterol-fed rabbits in 1913, and recounts the endeavours and achievements of the leading actors in this protracted scientific drama. The cast is drawn from an extraordinary variety of scientific disciplines: pathology, biophysics, epidemiology, nutrition, cardiology, lipidology, genetics, microbiology, pharmacology, and clinical trial design. Most of the scientists believed that cholesterol played a causal role in atherosclerosis and cardiovascular disease, but there were some who dissented strongly from this conclusion. The breadth of scientific disciplines involved in proving the lipid hypothesis is matched by the geographical spread of the participants. Anitschkow worked in Russia, Endo discovered the first statin in Japan, their commercial development by Merck took place in the USA and evidence of benefit from lowering cholesterol came from trials conducted in Scandinavia and the UK. The subsequent meta-analysis of these statin trials in 2005 proved the validity of the lipid hypothesis beyond any doubt. The history of how this all came about and its impact upon health policy and medical practice is recalled here in Resolving the Cholesterol Controversy.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Éditeur
WSPC (EUROPE)
Date d'édition
2023
Langue
anglais
ISBN 10 
1800615876
ISBN 13 
9781800615878
Reliure
Broché
Nombre de pages
246
Coordonnées du fabricant
non disponible
Personne responsable
gpsr@libri.de
gpsr@libri.de

Friedensallee 273
Hamburg
22763
Allemagne

Autres éditions populaires du même titre

9781800613973: Resolving The Cholesterol Controversy: The Scientists Who Proved The Lipid Hypothesis Of Causation Of Atherosclerosis And Coronary Heart Disease

Edition présentée

ISBN 10 :  1800613970 ISBN 13 :  9781800613973
Editeur : WSPC (EUROPE), 2023
Couverture rigide