Computing for Comparative Microbial Genomics: Bioinformatics for Microbiologists - Couverture rigide

Ussery, David Wayne; Wassenaar, Trudy M.; Borini, Stefano

 
9781848002548: Computing for Comparative Microbial Genomics: Bioinformatics for Microbiologists

Synopsis

Overview and Goals This book describes how to visualize and compare bacterial genomes. Sequencing technologies are becoming so inexpensive that soon going for a cup of coffee will be more expensive than sequencing a bacterial genome. Thus, there is a very real and pressing need for high-throughput computational methods to compare hundreds and thousands of bacterial genomes. It is a long road from molecular biology to systems biology, and in a sense this text can be thought of as a path bridging these ? elds. The goal of this book is to p- vide a coherent set of tools and a methodological framework for starting with raw DNA sequences and producing fully annotated genome sequences, and then using these to build up and test models about groups of interacting organisms within an environment or ecological niche. Organization and Features The text is divided into four main parts: Introduction, Comparative Genomics, Transcriptomics and Proteomics, and ? nally Microbial Communities. The ? rst ? ve chapters are introductions of various sorts. Each of these chapters represents an introduction to a speci? c scienti? c ? eld, to bring all readers up to the same basic level before proceeding on to the methods of comparing genomes. First, a brief overview of molecular biology and of the concept of sequences as biological inf- mation are given.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

The problem many microbiologists face is simply that of too much information. Built around teaching computational and bioinformatic methodology, this book details published methods for comparing genomes and provides examples of how to make custom comparisons.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Autres éditions populaires du même titre

9781849967631: Computing for Comparative Microbial Genomics: Bioinformatics for Microbiologists

Edition présentée

ISBN 10 :  1849967636 ISBN 13 :  9781849967631
Editeur : Springer, 2010
Couverture souple