Synopsis
While there have been books on both physics, and radiobiology applied to radiotherapy published before, there is a lack of books presenting the two aspects of cancer treatment with radiation (as supported by clinical trials) in a single volume. In addition, none of the books currently available on the market, either on radiotherapy or radiobiology, provides any basic summary or evaluation of major clinical trials, and comprehensive updates on the latest trials are also not available. Radiobiology is the science behind radiotherapy, therefore this book presents the rationale for using radiation in various modalities and schedules for a diversity of tumours.Starting with an introduction to both radiotherapy and radiobiology, the book continues with the major aspects of radiotherapy (types of radiation, apparatus used in the treatment process, conventional treatment modalities, unconventional treatment methods, dosimetry) and radiobiology (biological effects of radiation, tumour characteristics and behaviour during treatment, normal tissue toxicity, models in radiobiology). Each chapter is designed with the three disciplines in mind, illustrating their relationship, explaining the basic science, showing the role of radiobiology in the development of radiotherapy and discussing evidence provided by clinical trials.Modern radiotherapy strongly relies on physics and technology when delivering radiation as well as on cell biology when assessing tumour and normal tissue response to radiation. The authors all lecture on these subjects (both undergraduate and postgraduate levels) and this book book will provide the required textbook. Additionally the authors also work in the clinical environment of a major teaching hospital where they have good hands-on experience. This clinical and technical know-how of individual physical, biological and clinical aspects of various radiotherapy treatment techniques will be included in the book.
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Biographie de l'auteur
A/Prof Loredana Marcu has a Masters Degree in Applied Physics and a PhD in Medical Physics/Radiobiology. She has been lecturing since 1995, and previously published two books on Mechanics and Teaching methodologies, respectively. She was awarded the title Eminent Scientist of the year 2004 by the International Council for Research and is the recipient of the Boyce Worthley award 2006 given by the Australasian College of Physical Scientists and Engineers in Medicine for her achievements in the areas of radiobiology and medical physics. A/Prof Eva Bezak has an MSc in both Nuclear and Medical Physics and a PhD in applied Nuclear/Radiation Physics. She has been lecturing on radiation and radiotherapy physics since 1999, and has supervised 13 postgraduate students in radiotherapy physics. She is accredited by the Australasian College of Physical Scientists and Engineers in Medicine (AC PSEM) in Radiotherapy Equipment Commissioning and Quality Assurance (2004) and was nominated for the 2003 National Awards for Outstanding Women in Non-Traditional Areas of Work and Study. Prof Barry Allen is a biomedical physicist and Conjoint Professor of the St George Clinical School, UNSW. Previously, he worked at ANSTO as a Chief Research Scientist. In the early 1980s Prof Allen turned his attention to the application of neutrons in medicine. He went on to become President of the International Society for Neutron Capture Therapy and to convene the Fourth International Symposium in Sydney in 1990. Prof Allen made the first human body protein measurements in Australia, in collaboration with Sydney hospitals. He has published more than 300 papers, and was elected President of the Asia Oceania Federation of Medical Physics and President of the International Organisation of Medical Physics in 2006. He was elected Vice President of the International Union for Physical and Engineering Science in Medicine and is Chair, Health Technology and Training Task Group of the IUPESM.
Présentation de l'éditeur
The scientific and clinical foundations of Radiation Therapy are cross-disciplinary. This book endeavours to bring together the physics, the radiobiology, the main clinical aspects as well as available clinical evidence behind Radiation Therapy, presenting mutual relationships between these disciplines and their role in the advancements of radiation oncology.
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