Synopsis
Contents: Genetic and Epigenetic Aspects of Bone Development.- Tissue Interactions in Early Long Bone Development.- The Epiphyseal Growth Plate.- Hedgehog Signaling in Growth Plate and Bone Development.- microRNA Role in Skeletal Development.- FGF/FGFR Signaling in Skeletal Dysplasias.- The Role of Hypoxia-Induced Factors.- BMP Signaling in Skeletogenesis.- Wnt Signaling in Bone Development.- Development of the Cranio-Facial Complex.- Dentin and Bone: Similar Collagenous Mineralized Tissues.- Evolution of Bone Proteins.- Osteogenesis Imperfecta.- Fibrodysplasia Ossificans Progressiva: Developmental Implications of a Novel Metamorphogene.- Bone-Mineral Homeostasis and Associated Pathologies.- Interrelationship between Bone and Other Tissues: Brain-bone Axis and Bone-adipo Axis.- Mechanobiology of Bone Development and Computational Simulations.
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Bone and Development (Topics in Bone Biology, 6)
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Springer, 2010
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ISBN 13 : 9781848828216
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hardcover. Etat : Good. Connecting readers with great books since 1972! Used textbooks may not include companion materials such as access codes, etc. May have some wear or writing/highlighting. We ship orders daily and Customer Service is our top priority! N° de réf. du vendeur S_335383196
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Bone and Development.
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London, Springer., 2010
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66 illus., 44 in color, XXVII, 305 p. Hardcover. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Stamped. Topics in Bone Biology, Vol. 6. Sprache: Englisch. N° de réf. du vendeur 908IB
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Bone and Development
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Etat : Sehr gut. Zustand: Sehr gut | Seiten: 336 | Sprache: Englisch | Produktart: Bücher | This book, Vol. 6 in the series Topics in Bone Biology, deals with bone develop ment from growth to mineralization. Understanding tissue dev- opment involves combining embryological and histological information with the increasing knowledge from molecular and genetic studies. In each developmental stage, some genes are expressed and others silenced. Disease, especially disease progression, also is characterized by changes in gene expression that then are transmitted to daughter cells. In both situations, the choreography of gene expression and partial or complete silencing often are the result of the interaction between the genome and the epi- nome, i.e., between a very stable set of structures and rapidly changing environmental factors. Chapter 1, by O¿Connor, Farach-Carson, and Schanen, is an overview of the feld and of topics discussed in greater detail in subsequent chapters. After discussing bone development in terms of intramembranous and en- chondral ossifcation, the chapter describes gene expression in osteoblasts and osteoclasts, bone cell coupling, and the regulatory effects of steroid h- mones. Primary genetic defects that lead to various bone diseases ¿ Marfan¿s syndrome, Paget¿s disease, and juvenile osteoporosis, among others ¿ are analyzed. The chapter ends with a section on the epigenetic regulation of bone development, including methylation, histone modifcations, and imprinting. This chapter, like all others, has an extensive bibliography and fgures to illustrate principal points. N° de réf. du vendeur 5684048/12
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Gebunden. Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Genetic and Epigenetic Aspects of Bone Development.- Tissue Interactions in Long Bone Development.- The Epiphyseal Growth Plate.- Hedgehog Signaling in Growth Plate and Bone Development.- Role of microRNA in Skeleton Development.- FGF/FGFR Signaling in Skel. N° de réf. du vendeur 4287121
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Etat : New. pp. xii + 300 66 Illus. (44 Col.). N° de réf. du vendeur 6528029
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Bone and Development
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Springer London Apr 2010, 2010
ISBN 10 : 1848828217
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Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume, the sixth in the series Topics in Bone Biology, presents the current knowledge of bone development, from growth to mineralization. Like previous volumes in this series, it embraces the important interaction between medical science and practice. Insights stemming from molecular and cellular events are applied to the clinical setting, providing a deeper understanding of bone development complications for the practicing clinician, whilst informing bone scientists of the advancements in their field and the wider applications of their research. Covering a diverse and current range of topics, including the genetic and epigenetic aspects of bone development, cell signaling in growth plate and bone development, evolution of bone proteins and the interrelationship between bone and other tissues, this volume provides a thorough look at bone development biology. The contributing authors to this volume are acknowledged authorities in their fields. In addition, the extensive lists of references point the reader to further information on any of the topics covered. Clinicians and researchers involved in child development and therapy will find this book a valuable addition to their libraries. 336 pp. Englisch. N° de réf. du vendeur 9781848828216
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Bone and Development
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Springer London, Springer London Apr 2010, 2010
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ISBN 13 : 9781848828216
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Buch. Etat : Neu. Neuware -This book, Vol. 6 in the series Topics in Bone Biology, deals with bone develop ment from growth to mineralization. Understanding tissue dev- opment involves combining embryological and histological information with the increasing knowledge from molecular and genetic studies. In each developmental stage, some genes are expressed and others silenced. Disease, especially disease progression, also is characterized by changes in gene expression that then are transmitted to daughter cells. In both situations, the choreography of gene expression and partial or complete silencing often are the result of the interaction between the genome and the epi- nome, i.e., between a very stable set of structures and rapidly changing environmental factors. Chapter 1, by O¿Connor, Farach-Carson, and Schanen, is an overview of the feld and of topics discussed in greater detail in subsequent chapters. After discussing bone development in terms of intramembranous and en- chondral ossifcation, the chapter describes gene expression in osteoblasts and osteoclasts, bone cell coupling, and the regulatory effects of steroid h- mones. Primary genetic defects that lead to various bone diseases ¿ Marfan¿s syndrome, Paget¿s disease, and juvenile osteoporosis, among others ¿ are analyzed. The chapter ends with a section on the epigenetic regulation of bone development, including methylation, histone modifcations, and imprinting. This chapter, like all others, has an extensive bibliography and fgures to illustrate principal points.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 336 pp. Englisch. N° de réf. du vendeur 9781848828216
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Bone and Development
Edité par
Springer London, Springer London, 2010
ISBN 10 : 1848828217
ISBN 13 : 9781848828216
Neuf
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Buch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume, the sixth in the series Topics in Bone Biology, presents the current knowledge of bone development, from growth to mineralization. Like previous volumes in this series, it embraces the important interaction between medical science and practice. Insights stemming from molecular and cellular events are applied to the clinical setting, providing a deeper understanding of bone development complications for the practicing clinician, whilst informing bone scientists of the advancements in their field and the wider applications of their research. Covering a diverse and current range of topics, including the genetic and epigenetic aspects of bone development, cell signaling in growth plate and bone development, evolution of bone proteins and the interrelationship between bone and other tissues, this volume provides a thorough look at bone development biology. The contributing authors to this volume are acknowledged authorities intheir fields. In addition, the extensive lists of references point the reader to further information on any of the topics covered. Clinicians and researchers involved in child development and therapy will find this book a valuable addition to their libraries. N° de réf. du vendeur 9781848828216
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