Glial Cell Development: Basic Principles and Clinical Relevance - Couverture rigide

Couverture rigide

ISBN 10 : 1872748546 ISBN 13 : 9781872748542

Editeur : Bios Scientific Publishers Ltd, 1995

Synopsis

Glial cell function and development have now become a major focus of research in the neurosciences. Distinct glial progenitors have been identified, key glial genes have been cloned and the growth factor regulation of glial survival, proliferation and function is being unravelled. as a result, it will soon be possible to understand, at the molecular level, some vital glial functions, such as myelination and regulation of axon growth and repair. From the viewpoint of neuropathology, these studies provide exciting clues about how glial cells might be involved in nervous system disorders. This should result in the development of therapeutic strategies involving the transplantation of normal or genetically modified glial cells into damaged nervous tissue. In this book, leading researchers review recent advances in the knowledge of all classes of glia, and describes how this knowledge is now being harnessed for the treatment of human disease.

A propos du livre

Présentation de l'éditeur

This is a new edition in the Cellular and Molecular Neurobiology series. The majority of cells in the nervous system are glial cells. During development, these cells provide growth factors that stimulate the proliferation, migration and survival of neurones and their precursors, and promote and guide axonal growth. In the mature nervous system, glial cells provide insulating myelin sheath around axons and provide metabolic and structural support for neurones. Glial cells also have a major influence on the local response to injury of central nerve tracts and the peripheral nervous system, either promoting, or inhibiting, axonal regrowth and recovery of lost function. This book provides a comprehensive, state-of-the-art overview of research into the development, function and malfunction of glial cells. It offers a compelling insight into how basic research throws light onto diseases and disorders and points the way towards treatments. Teams of internationally renowned experts, all active in research, have contributed chapters.

Détails de l'édition

• Éditeur: Bios Scientific Publishers Ltd
• Date d'édition: 1995
• Langue: anglais
• ISBN 10: 1872748546
• ISBN 13: 9781872748542
• Reliure: Relié
• Nombre de pages: 256
• Éditeur: Jessen Kristjan R., Richardson William D.
• Coordonnées du fabricant: non disponible
• Personne responsable: Messaggerie Libri; ufficio.anagrafiche@meli.it; ; Via Verdi, 8; Assago Milano; Italie