Computer-Aided Vaccine Design - Couverture rigide

Tong, Joo Chuan; Ranganathan, Shoba

Couverture rigide

ISBN 10 : 1907568417 ISBN 13 : 9781907568411

Editeur : Woodhead Publishing Ltd, 2013

Synopsis

Computational pre-screening of antigens is now routinely applied to the discovery of vaccine candidates. Computer-aided vaccine design is a comprehensive introduction to this exciting field of study. The book is intended to be a textbook for researchers and for courses in bioinformatics, as well as a laboratory reference guide. It is written mainly for biologists who want to understand the current methods of computer-aided vaccine design. The contents are designed to help biologists appreciate the underlying concepts and algorithms used, as well as limitations of the methods and strategies for their use. The book is of interest to computational biologists who would like to understand more about the biological concepts related to the field of computational immunology.

Key Features: essential reading for any biologist who wants to understand methods of computer-aided vaccine design; description of available data sources and publicly available software, with detailed analysis of strengths and weaknesses; theoretical concepts and practical examples of database design and development for a virtual screening campaign.

Contents: MHC and T cell responses; Immunoglobulins and B cell responses; Scientific publications and databases; Database design; Computational T cell vaccine design; Computational B cell vaccine design; Infectious disease informatics; Vaccine safety and quality assessments; Vaccine adjuvant informatics.

A propos du livre

À propos de l'auteur

Dr Joo Chuan Tong is a Senior Scientist at the A*STAR Institute of High Performance Computing, Singapore. He is an Adjunct Assistant Professor at the Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore. Dr. Tong has won numerous awards, including the MIT TR35 Award in 2008 and Singapore Youth Award (Science and Technology) in 2009, and is the only Asian on the Senior Innovation Advisory Board of Pfizer Inc, the world s largest research-based pharmaceutical company, at their world headquarters in New York, USA. Professor Shoba Ranganathan is Chair Professor of Bioinformatics at Macquarie University, Australia. She is Adjunct Professor at the National University of Singapore. Her research focusses on bioinformatics analysis at the genome, transcriptome and proteome levels. She holds a doctorate in Chemistry from the Indian Institute of Technology, Delhi, India, and has trained in biocomputing at the Institut de Biologie Physico-Chimique in Paris and at the University of New Orleans, USA . She was the first Australian Director elected to the Board of the International Society for Computational Biology (ISCB) and is currently the President, Asia-Pacific Bioinformatics Network (APBionet) and Steering Committee member of the International Immunomics Society.

Détails de l'édition

• Éditeur: Woodhead Publishing Ltd
• Date d'édition: 2013
• Langue: anglais
• ISBN 10: 1907568417
• ISBN 13: 9781907568411
• Reliure: Relié
• Numéro d'édition: 1
• Nombre de pages: 164
• Coordonnées du fabricant: non disponible
• Personne responsable: LSWR Group; b.criscuolo@lswr.it; ; Via Spadolini, 7; Milano; Italie