Articles liés à Angiogenesis: Biology and Pathology

Angiogenesis: Biology and Pathology - Couverture rigide

 
9781936113439: Angiogenesis: Biology and Pathology
Couverture rigide
ISBN 10 : 1936113430 ISBN 13 : 9781936113439
Editeur : Cold Spring Harbor Laboratory Press,U.S., 2011

Synopsis

Angiogenesis is the process by which new blood vessels are generated from preexisting vessels. It is vital for proper embryonic development, patterning of the vascular system, and wound healing. It is rate limiting in cancer progression, because the formation of new blood vessels is essential for growth and survival of tumors.Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine reviews the mechanisms of angiogenesis that operate in normal development and in diseases such as cancer. The contributors review the biology of endothelial cells, describing the specific roles of tip and stalk cells in vessel sprouting and lumen formation. They discuss the key angiogenic regulators (e.g., vascular endothelial growth factor [VEGF]), as well as antiangiogenic agents including microRNAs, thrombospondins, and semaphorins. Therapeutic approaches that target pathological angiogenesis, such as the ongoing clinical trials of anti-VEGF drugs, are also covered.This volume, which includes discussions of other vascular dysfunctions (e.g., arteriovenous malformations) and comparisons between the blood vascular system and the lymphatic system, is a vital reference for developmental and cancer biologists, as well as anyone seeking to understand the biology and pathology of the vascular system.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Angiogenesis is the process by which new blood vessels are generated from preexisting vessels. It is vital for proper embryonic development, patterning of the vascular system, and wound healing. It is rate limiting in cancer progression, because the formation of new blood vessels is essential for growth and survival of tumors.Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine reviews the mechanisms of angiogenesis that operate in normal development and in diseases such as cancer. The contributors review the biology of endothelial cells, describing the specific roles of tip and stalk cells in vessel sprouting and lumen formation. They discuss the key angiogenic regulators (e.g., vascular endothelial growth factor [VEGF]), as well as antiangiogenic agents including microRNAs, thrombospondins, and semaphorins. Therapeutic approaches that target pathological angiogenesis, such as the ongoing clinical trials of anti-VEGF drugs, are also covered.This volume, which includes discussions of other vascular dysfunctions (e.g., arteriovenous malformations) and comparisons between the blood vascular system and the lymphatic system, is a vital reference for developmental and cancer biologists, as well as anyone seeking to understand the biology and pathology of the vascular system.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
Cold Spring Harbor Laboratory Press,U.S.
Date d'édition
2011
Langue
anglais
ISBN 10 
1936113430
ISBN 13 
9781936113439
Reliure
Relié
Numéro d'édition
1
Nombre de pages
522
Éditeur
Klagsbrun Michael, D'Amore Patricia
Coordonnées du fabricant
non disponible
Personne responsable
GPSR Kontakt
gpsr@libri.de

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