Catalytically Active Nucleic Acids - Couverture souple

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9783030296483: Catalytically Active Nucleic Acids

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ISBN 10 : 3030296482 ISBN 13 : 9783030296483

Editeur : Springer, 2020

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Highlights fundamental aspects of nucleic acids enzymes

Addresses methods and applications

Discusses challenges in and prospects for nucleic acid enzyme engineering

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� propos de l?auteur

Harald Seitz has been a group leader at the Fraunhofer Institute for Cell Therapy and Immunology, Branch Bioanalytics and Bioprocesses in Potsdam-Golm since 2012. He received his PhD (2000) and Diploma (1997) from the Free University Berlin and his postdoctoral degree (Habilitation (2012) from the University of Kassel. He worked for more than 10 years at Max-Planck Institute for Molecular Genetics in Berlin and moved in 2012 to the Fraunhofer Institute for Cell Therapy and Immunology, Branch Bioanalytics and Bioprocesses. His work chiefly focuses on the (bio)analysis of different samples such as human serum or environmental samples using a variety of methods.

Les informations fournies dans la section � A propos du livre � peuvent faire r�f�rence � une autre �dition de ce titre.

�diteur: Springer
Date d'�dition: 2020
Langue: anglais
ISBN 10: 3030296482
ISBN 13: 9783030296483
Reliure: Broch�
Num�ro d'�dition: 1
Nombre de pages: 132
�diteur: Seitz Harald, Stahl Frank, Walter Johanna-Gabriela
Coordonn�es du fabricant: ProductSafety@springernature.com
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Catalytically Active Nucleic Acids (eng)

Seitz, Harald

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Catalytically Active Nucleic Acids

Seitz, Harald|Stahl, Frank|Walter, Johanna-Gabriela

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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Highlights fundamental aspects of nucleic acids enzymesAddresses methods and applications Discusses challenges in and prospects for nucleic acid enzyme engineeringHarald Seitz has been a group leader at the Frau. N� de r�f. du vendeur 448678166

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Catalytically Active Nucleic Acids

Seitz, Harald (EDT); Stahl, Frank (EDT); Walter, Johanna-Gabriela (EDT)

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Catalytically Active Nucleic Acids

Harald Seitz

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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume reviews numerous reaction mechanisms and applications of nucleic acids with catalytic activity. Written by an interdisciplinary team of authors, it provides an essential overview of these acids' fundamental aspects, while also addressing associated methodologies such as nucleic acid enzyme engineering, peroxidase-mimicking DNAzymes and Aptazymes.After the discovery of natural ribozymes - RNA molecules that mediate the cleavage and formation of phosphodiester bonds and the formation of peptide bonds - numerous artificial ribozymes with altered catalytic activities were produced by in vitro and in vivo selection. Unlike ribozymes, DNAzymes do not occur in nature. Although the catalytic activity of nucleic acid enzymes is usually much slower than that of proteins, nucleic acid enzymes with comparable catalytic activity have been obtained using stringent selection processes. The key advantages of these enzymes: they are e.g. smaller, easier to produce and purify than proteins, and can withstand denaturation, e.g. by heat.Over the last few years, the number of publications on the applications of enzymatic nucleic acids has grown steadily. Summarizing the fundamentals and applications of these acids, this book will not only be an excellent resource for experts in the field but will also guide young researchers just starting out in this significant area. 132 pp. Englisch. N� de r�f. du vendeur 9783030296483

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Catalytically Active Nucleic Acids

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Catalytically Active Nucleic Acids

Seitz, Harald (EDT); Stahl, Frank (EDT); Walter, Johanna-Gabriela (EDT)

Edit� par Springer, 2020

ISBN 10 : 3030296482 ISBN 13 : 9783030296483

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Catalytically Active Nucleic Acids

Harald Seitz

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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Highlights fundamental aspects of nucleic acids enzymesAddresses methods and applicationsDiscusses challenges in and prospects for nucleic acid enzyme engineeringSpringer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 132 pp. Englisch. N� de r�f. du vendeur 9783030296483

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Catalytically Active Nucleic Acids

Harald Seitz

Edit� par Springer International Publishing, 2020

ISBN 10 : 3030296482 ISBN 13 : 9783030296483

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Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume reviews numerous reaction mechanisms and applications of nucleic acids with catalytic activity. Written by an interdisciplinary team of authors, it provides an essential overview of these acids' fundamental aspects, while also addressing associated methodologies such as nucleic acid enzyme engineering, peroxidase-mimicking DNAzymes and Aptazymes.After the discovery of natural ribozymes - RNA molecules that mediate the cleavage and formation of phosphodiester bonds and the formation of peptide bonds - numerous artificial ribozymes with altered catalytic activities were produced by in vitro and in vivo selection. Unlike ribozymes, DNAzymes do not occur in nature. Although the catalytic activity of nucleic acid enzymes is usually much slower than that of proteins, nucleic acid enzymes with comparable catalytic activity have been obtained using stringent selection processes. The key advantages of these enzymes: they are e.g. smaller, easier to produce and purify than proteins, and can withstand denaturation, e.g. by heat.Over the last few years, the number of publications on the applications of enzymatic nucleic acids has grown steadily. Summarizing the fundamentals and applications of these acids, this book will not only be an excellent resource for experts in the field but will also guide young researchers just starting out in this significant area. N� de r�f. du vendeur 9783030296483

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