Articles liés à Biophysical and Computational Tools in Drug Discovery

Biophysical and Computational Tools in Drug Discovery - Couverture rigide

Livre 36 sur 38: Topics in Medicinal Chemistry
 
9783030852801: Biophysical and Computational Tools in Drug Discovery
Couverture rigide
ISBN 10 : 3030852806 ISBN 13 : 9783030852801
Editeur : Springer Nature Switzerland AG, 2021

Synopsis

This book reviews recent physicochemical and biophysical techniques applied in drug discovery research, and it outlines the latest advances in computational drug design. Divided into 10 chapters, the book discusses about the role of structural biology in drug discovery, and offers useful application cases of several biophysical and computational methods, including time-resolved fluorometry (TRF) with Förster resonance energy transfer (FRET), X-Ray crystallography, nuclear magnetic resonance spectroscopy, mass spectroscopy, generative machine learning for inverse molecular design, quantum mechanics/molecular mechanics (QM/MM,ONIOM) and quantum molecular dynamics (QMT) methods. Particular attention is given to computational search techniques applied to peptide vaccines using novel mathematical descriptors and structure and ligand-based virtual screening techniques in drug discovery research. Given its scope, the book is a valuable resource for students, researchers and professionals frompharmaceutical industry interested in drug design and discovery.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

À propos de l'auteur

Dr. Anil K. Saxena, Emeritus Scientist, Ex-Chief Scientist Central Drug Research Institute, Lucknow, India, is actively involved in the fields of Medicinal Chemistry & Computer Aided Drug Design (CADD). With 50+ years of research experience, several publications in journals and books, and 70 patents, he is the recipient of numerous awards, including the Alexander von Humboldt Fellowship, INSA Young Scientist Medal , Themis Chemicals UDCT Diamond Jubilee Distinguished Fellowship, Ranbaxy Research Award in Pharmaceutical Sciences, an Honorary Medal for outstanding contributions to Medicinal Chemistry and International Scientific collaboration Moscow, Russia, 2004, and Prof. P.K. Bose Memorial Award (Indian Chemical Society, 2009). Dr. Saxena is a Fellow of the Royal Society of Chemistry, UK, and is also series editor of “Topics in Medicinal Chemistry” published by Springer. He is the Editorial Board Member of different journals like Medicinal Chemistry Research, SAR and QSAR in Environmental Research, Current Topics in Medicinal Chemistry and online International journal ARKIVOC, and he is also member of several committees including the American Chemical Society.

 

 


À propos de la quatrième de couverture

This book reviews recent physicochemical and biophysical techniques applied in drug discovery research, and it outlines the latest advances in computational drug design. Divided into 10 chapters, the book discusses about the role of structural biology in drug discovery, and offers useful application cases of several biophysical and computational methods, including time-resolved fluorometry (TRF) with Förster resonance energy transfer (FRET), X-Ray crystallography, nuclear magnetic resonance spectroscopy, mass spectroscopy, generative machine learning for inverse molecular design, quantum mechanics/molecular mechanics (QM/MM, ONIOM) and quantum molecular dynamics (QMT) methods. Particular attention is given to computational search techniques applied to peptide vaccines using novel mathematical descriptors and structure and ligand-based virtual screening techniques in drug discovery research. Given its scope, the book is a valuable resource for students, researchers and professionals frompharmaceutical industry interested in drug design and discovery.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
Springer Nature Switzerland AG
Date d'édition
2021
Langue
anglais
ISBN 10 
3030852806
ISBN 13 
9783030852801
Reliure
Relié
Numéro d'édition
1
Nombre de pages
402
Éditeur
Saxena Anil Kumar
Coordonnées du fabricant
ProductSafety@springernature.com
ProductSafety@springernature.com

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