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Clinical Utility of Applying PGx and Deprescribing-Based Decision Support in Polypharmacy - Couverture rigide
Synopsis
Polypharmacy is a necessary and important aspect of drug treatment; however, it becomes a challenge when the medication risks outweigh the benefits for an individual patient. Drug-drug interactions and the introduction of prescribing cascades are common features of polypharmacy, which can lead to ineffectiveness and increased risk of adverse drug reactions (ADR). Genes encoding CYP450 isozymes and other drug-related biomarkers have attracted considerable attention as targets for pharmacogenetic (PGx) testing due to their impact on drug metabolism and response. This Special Issue is devoted to explore the status and initiatives taken to circumvent ineffectiveness and to improve medication safety for polypharmacy patients. Specific areas include drug-drug interactions and consequences thereof in therapeutic management, including PK- and PD-profiling; the application of PGx-based guidance and/or decision tools for drug-gene and drug-drug gene interactions; medication reviews; development and application of deprescribing tools; and drivers and barriers to overcome for successful implementation in the healthcare system.
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- ÉditeurMdpi AG
- Date d'édition2022
- ISBN 10 303655162X
- ISBN 13 9783036551623
- ReliureRelié
- Langueanglais
- Nombre de pages224
- ÉditeurVermehren Charlotte, Westergaard Niels
- Coordonnées du fabricantnon disponible
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Gebunden. Etat : New. KlappentextrnrnPolypharmacy is a necessary and important aspect of drug treatment however, it becomes a challenge when the medication risks outweigh the benefits for an individual patient. Drug-drug interactions and the introduction of prescrib. N° de réf. du vendeur 726146590
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Buch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Polypharmacy is a necessary and important aspect of drug treatment; however, it becomes a challenge when the medication risks outweigh the benefits for an individual patient. Drug-drug interactions and the introduction of prescribing cascades are common features of polypharmacy, which can lead to ineffectiveness and increased risk of adverse drug reactions (ADR). Genes encoding CYP450 isozymes and other drug-related biomarkers have attracted considerable attention as targets for pharmacogenetic (PGx) testing due to their impact on drug metabolism and response. This Special Issue is devoted to explore the status and initiatives taken to circumvent ineffectiveness and to improve medication safety for polypharmacy patients. Specific areas include drug-drug interactions and consequences thereof in therapeutic management, including PK- and PD-profiling; the application of PGx-based guidance and/or decision tools for drug-gene and drug-drug gene interactions; medication reviews; development and application of deprescribing tools; and drivers and barriers to overcome for successful implementation in the healthcare system. N° de réf. du vendeur 9783036551623
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Clinical Utility Of Applying Pgx And Deprescribing-Based Decision Support In Polypharmacy
Edité par
Mdpi AG, 2022
ISBN 10 : 303655162X
ISBN 13 : 9783036551623
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Couverture rigide
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