Gastrointestinal Variables and Drug Absorption: Experimental, Computational and In Vitro Predictive Approaches - Couverture souple

 
9783039284924: Gastrointestinal Variables and Drug Absorption: Experimental, Computational and In Vitro Predictive Approaches
Couverture souple
ISBN 10 : 3039284924 ISBN 13 : 9783039284924
Editeur : Mdpi AG, 2020

Synopsis

This book presents some of the state-of-the-art methods for the study of the gastrointestinal variables affecting oral drug absorption. Practical applications of new in vitro release/dissolution methods are presented, as well as in vitro permeability studies to explore segmental differences. The application of MRI methods for the study of colon physiology is presented to illustrate its potential applications in controlled release dosage form design. Some examples of successful in vitro-in vivo correlations show how implementing the gastrointestinal physiological variables in the new in vitro methods can improve the predictions of in vivo drug product performance. The book contains an updated review of the experimental, computational, and in vivo approaches for measuring intestinal permeability.

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Éditeur
Mdpi AG
Date d'édition
2020
Langue
anglais
ISBN 10 
3039284924
ISBN 13 
9783039284924
Reliure
Broché
Nombre de pages
206
Éditeur
Bermejo Marival
Coordonnées du fabricant
non disponible
Personne responsable
non disponible