New Aspects of Cancer Stem Cell Biology: Implications for Innovative Therapies - Couverture rigide

Couverture rigide

ISBN 10 : 3039434063 ISBN 13 : 9783039434060

Editeur : Mdpi AG, 2020

Synopsis

The cancer stem cell (CSC) paradigm represents one of the most prominent breakthroughs of the last decades in tumor biology. CSCs are that subpopulation within a tumor that can survive conventional therapies and as a consequence are able to fuel tumor recurrence. Nevertheless, the biological characteristics of CSCs and even their existence, remain the main topic among tumor biologists debates. The difficulty in achieving a better definition of CSC biology may actually be explained by the plasticity of such a cell subpopulation. Indeed, the emerging view is that CSCs represent a dynamic "state" of tumor cells that can acquire stemness-related properties under specific circumstances, rather than referring to a well-defined group of cells. Regardless of their origin, it is clear that designing novel antitumor treatments based on the eradication of CSCs will only be possible upon unraveling the biological mechanisms that underlie their pathogenic role in tumor progression and therapy resistance. The Special Issue on "New aspects of cancer stem cell biology: implications for innovative therapies" aims at highlighting recent insights into CSC features that can make them an attractive target for novel therapeutic strategies.

Détails de l'édition

• Éditeur: Mdpi AG
• Date d'édition: 2020
• Langue: anglais
• ISBN 10: 3039434063
• ISBN 13: 9783039434060
• Reliure: Relié
• Nombre de pages: 208
• Éditeur: Cavallaro Ugo, Giordano Marco
• Coordonnées du fabricant: non disponible
• Personne responsable: gpsr@libri.de; gpsr@libri.de; ; Friedensallee 273; Hamburg; 22763; Allemagne