This volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts ranging from human cancers to cardiovascular disease and ageing. The role of lncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, past retroelements integrated within the human genome, as well as the role these pseudogene-derived lncRNAs play in cancer development are discussed in detail. Further, the book examines the function of lncRNAs in diseases such as diabetes, in smooth muscle formation, and in the modulation of nuclear receptors, as well as in connection with perspectives on the development of personalized therapeutics. It offers an appealing and insightful resource for scientists and clinicians alike.
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Kevin Morris is an Associate Professor at the Department of Molecular and Experimental Medicine, The Scripps Research Institute in La Jolla, CA, USA. The responsible series editor is Peter K. Vogt, The Scripps Research Institute in La Jolla, CA, USA.
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Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Thisvolume focuses on the roles of long non-coding RNAs (lncRNAs) in contextsranging from human cancers to cardiovascular disease and ageing. The role oflncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, pastretroelements integrated within the human genome, as well as the role thesepseudogene-derived lncRNAs play in cancer development are discussed in detail. Further,the book examines the function of lncRNAs in diseases such as diabetes, in smoothmuscle formation, and in the modulation of nuclear receptors, as well as inconnection with perspectiveson the development ofpersonalized therapeutics. It offers an appealing and insightful resource forscientists and clinicians alike. 272 pp. Englisch. N° de réf. du vendeur 9783319239064
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Gebunden. Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Summarizes the tremendousprogress made within the last decade in understanding the roles of lncRNA inhuman diseaseBridges the divide betweeninferring lncRNA mechanisms and targeting lncRNAs by means of rationaltherapeuticsStresses th. N° de réf. du vendeur 82438497
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