Epigenetic Advancements in Cancer - Couverture rigide

Couverture rigide

ISBN 10 : 3319249495 ISBN 13 : 9783319249490

Editeur : Springer International Publishing AG, 2016

Synopsis

This volume explores the epigenetic alterations and their association with various human cancers. Considering one of human cancer as an example, individual chapters are focused on defining the role of epigenetic regulators and underlying mechanisms in cancer growth and progression.

 

Epigenetic alteration including DNA methylation, histone modification, nucleosome positioning and non-coding RNAs expression are involved in a complex network of regulating expression of oncogenes and tumor suppressor genes and constitute an important event of the multistep process of carcinogenesis. Recent advances in the understanding of the epigenetic regulation and detailed information of these epigenetic changes in various cancers provide new avenues of advancements in diagnostics, prognostics, and therapies of this highly fatal disease.

A propos du livre

À propos de l'auteur

Manoj K. Mishra, Ph.D., is Associate Professor of Biology and founding Director of the cancer biology research and training program at Alabama State University. He has published over 25 articles, over 30 abstracts and poster exhibits, co-edited a book on Gene Regulation and Cancer, and has written over 5 book chapters. Dr. Mishra is on multiple ed boards, including the European Journal of Bioinformatics, Advances in Medical Informatics, and the International Journal of Experimental Medicine, to name a few.

Kumar S. Bishnupuri, Ph.D., is a Research Instructor in the Department of Medicine at Washington University School of Medicine. Dr. Bishnupuri has published over 16 articles, 4 book chapters, and 32 abstracts for conference symposia. He also serves as a scientific reviewer for several journals including Carcinogenesis, Frontiers in Bioscience, Cancer Biology and Therapy, Journal of Pathology, and more.

À propos de la quatrième de couverture

This volume explores the epigenetic alterations and their association with various human cancers. Considering one of human cancer as an example, individual chapters are focused on defining the role of epigenetic regulators and underlying mechanisms in cancer growth and progression.



Epigenetic alteration including DNA methylation, histone modification, nucleosome positioning and non-coding RNAs expression are involved in a complex network of regulating expression of oncogenes and tumor suppressor genes and constitute an important event of the multistep process of carcinogenesis. Recent advances in the understanding of the epigenetic regulation and detailed information of these epigenetic changes in various cancers provide new avenues of advancements in diagnostics, prognostics, and therapies of this highly fatal disease.

Détails de l'édition

• Éditeur: Springer International Publishing AG
• Date d'édition: 2016
• Langue: anglais
• ISBN 10: 3319249495
• ISBN 13: 9783319249490
• Reliure: Relié
• Numéro d'édition: 1
• Nombre de pages: 246
• Éditeur: Mishra Manoj K., Bishnupuri Kumar S.
• Coordonnées du fabricant: ProductSafety@springernature.com; ProductSafety@springernature.com; ; Europaplatz 3; Heidelberg; 69115; Allemagne