Biomolecular Imaging at High Spatial and Temporal Resolution In Vitro and In Vivo - Couverture souple

Sharp, Thomas Harry

 
9783319350233: Biomolecular Imaging at High Spatial and Temporal Resolution In Vitro and In Vivo
Couverture souple
ISBN 10 : 3319350234 ISBN 13 : 9783319350233
Editeur : Springer, 2016

Synopsis

As part of a collaboration between two different groups in chemistry and biochemistry, Thom Sharp presents here his thesis work on the development of new methods for cryoelectron microscopy. Throughout his Ph.D., Thom had to master a whole range of techniques including modelling, molecular biology and microscopy. Using these skills to tackle an outstanding problem, the pursuit of high-resolution structures of peptide-based materials, Thom highlights in this thesis his newly developed methods for analysing and processing this particular type of electron microscopy data. This thesis gives the first molecular description of a de-novo designed peptide-based material. In general, this research will have a huge impact on the peptide assembly field, and also in electron microscopy as it introduces new methods and approaches, all of which are Thom's inventions and are described in this thesis.

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À propos de l?auteur

Thom Sharp completed his bachelor's degree in Biochemistry at the University of Bristol, with a year spent a year working at AstraZeneca. He continued in Bristol for his PhD in bionanotechnology, which was performed under the supervision of Dek Woolfson, a protein design chemist, and Paul Verkade, an electron microscopist. Thom is currently at the University of Oxford, where he is developing DNA-templated protein arrays to increase the throughput of single-particle analysis.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
Springer
Date d'édition
2016
Langue
anglais
ISBN 10 
3319350234
ISBN 13 
9783319350233
Reliure
Broché
Nombre de pages
168
Coordonnées du fabricant
non disponible
Personne responsable
CMN Printpool Inh. Mathis Neumann
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ISBN 10 :  3319021583 ISBN 13 :  9783319021584
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Couverture rigide