AMP-activated Protein Kinase - Couverture rigide

Cordero

Couverture rigide

ISBN 10 : 3319435876 ISBN 13 : 9783319435879

Editeur : Springer, 2016

Synopsis

Part I: AMPK in health.- Structure and Regulation of AMPK.- AMPK Regulation of Carbohydrate Metabolism.- AMPK Regulation of Lipid Metabolism.- AMPK Regulation of Protein Metabolism.- AMPK Regulation of cell growth, apoptosis, autophagy and bioenergetics.- AMPK Regulation of immunology.- AMPK and Stem Cells.- Part II: AMPK in the diseases.- AMPK in metabolic diseases.- AMPK in neurodegenerative diseases.- AMPK in cardiovascular diseases.- AMPK in cancer.- AMPK in aging.- AMPK in musculoskeletal diseases and pain.- AMPK in pathogens.- Part III: Pharmacology of AMPK.- Metformin, new drugs and AMPK.- Small molecules and AMPK.- Nutraceutical compounds and AMPK.- Part IV: Methods of study in AMPK.- Animal models.- In vitro study methods.

A propos du livre

À propos de l'auteur

Mario D Cordero is Research Associate at the University of Sevilla, Laboratory of Biological Research. He studies the role of AMPK in the metabolic abnormalities of the central nervous system in psychiatric diseases, and the implication of AMPK in the mechanism of pain and inflammation. He is also involved in drug trials using AMPK activators in rare diseases.

Benoit Viollet leads a research team at the Institut Cochin, Paris, which studies the physiological role of AMPK in cellular energy balance and the integrated stress response such as exercise, as well as nutrient and hormonal signals. The work includes studies of the therapeutic opportunity of AMPK in metabolic abnormalities associated with type 2 diabetes and obesity.

Détails de l'édition

• Éditeur: Springer
• Date d'édition: 2016
• Langue: anglais
• ISBN 10: 3319435876
• ISBN 13: 9783319435879
• Reliure: Relié
• Nombre de pages: 536
• Coordonnées du fabricant: Springer Nature Customer Service Center GmbH; ProductSafety@springernature.com; ; Europaplatz 3; Heidelberg; 69115; Allemagne