How to Overcome the Antibiotic Crisis: Facts, Challenges, Technologies and Future Perspectives - Couverture rigide

Couverture rigide

ISBN 10 : 3319492829 ISBN 13 : 9783319492827

Editeur : Springer International Publishing AG, 2017

Synopsis

This volume focuses on antibiotics research, a field of topical significance for human health due to the worrying increase of nosocomial infections caused by multi-resistant bacteria. It covers several basic aspects, such as the evolution of antibiotic resistance and the influence of antibiotics on the gut microbiota, and addresses the search for novel pathogenicity blockers as well as historical aspects of antibiotics. Further topics include applied aspects, such as drug discovery based on biodiversity and genome mining, optimization of lead structures by medicinal chemistry, total synthesis and drug delivery technologies. Moreover, the development of vaccines as a valid alternative therapeutic approach is outlined, while the importance of epidemiological studies on important bacterial pathogens, the problems arising from the excessive use of antibiotics in animal breeding, and the development of innovative technologies for diagnosing the "bad bugs" are discussed in detail. Accordingly, the book will appeal to researchers and clinicians alike.

A propos du livre

À propos de l'auteur

Prof. Dr. Marc Stadler and Prof. Dr. Petra DerschHelmholtz Centre for Infection Research, Braunschweig, Germany

Détails de l'édition

• Éditeur: Springer International Publishing AG
• Date d'édition: 2017
• Langue: anglais
• ISBN 10: 3319492829
• ISBN 13: 9783319492827
• Reliure: Relié
• Numéro d'édition: 1
• Nombre de pages: 508
• Éditeur: Stadler Marc, Dersch Petra
• Coordonnées du fabricant: Springer Nature Customer Service Center GmbH; ProductSafety@springernature.com; ; Europaplatz 3; Heidelberg; 69115; Allemagne