Clear description of the current knowledge in genome organization
Exposes new concepts of the roles of nuclear pore complexes in genomic organization and genome protection/maintenance
A unique source of information on nuclear organization and dynamics in one location
Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.
Maximiliano D'Angelo, Ph.D., is Faculty of the Development, Aging and Regeneration Program and the Immunity and Pathogenesis Program at the Sanford Burnham Medical Discovery Institute in La Jolla, California. He is also member of the Tumor Initiation and Maintenance Program of the NCI-designated Cancer Center. Before moving to SBP, Dr. D'Angelo was a Principal investigator of the Cardiovascular Research Institute at the University of California San Francisco and Assistant Professor of the Department of Biochemistry & Biophysics. Dr. D'Angelo received his Ph.D. in molecular biology from the University of Buenos Aires, Argentina, and trained at The Scripps Research Institute and the Salk Institute for Biological before beginning his independent career. He has been Fellow of the Ellison Foundation and American Federation for Aging Research, Pew Latin American Fellow, Pew Biomedical Scholar and Scholar of the American Cancer Society.
Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.
Vendeur : Universitätsbuchhandlung Herta Hold GmbH, Berlin, Allemagne
viii, 240 p. Hardcover. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Sprache: Englisch. N° de réf. du vendeur 33502AB
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Vendeur : Brook Bookstore On Demand, Napoli, NA, Italie
Etat : new. Questo è un articolo print on demand. N° de réf. du vendeur 9bf19151e142b4a261f825324b9ef2af
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Vendeur : Ria Christie Collections, Uxbridge, Royaume-Uni
Etat : New. In. N° de réf. du vendeur ria9783319716121_new
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Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne
Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The three-dimensional organization of the DNA inside the eukaryotic cell nucleus has emerged a critical regulator of genome integrity and function. Increasing evidence indicates that nuclear pore complexes (NPCs), the large protein channels that connect the nucleus to the cytoplasm, play a critical role in the establishment and maintenance of chromatin organization and in the regulation of gene activity. These findings, which oppose the traditional view of NPCs as channels with only one: the facilitation of nucleocytoplasmic molecule exchange, have completely transformed our understanding of these structures. This book describes our current knowledge of the role of NPCs in genome organization and gene expression regulation. It starts by providing an overview of the different compartments and structures of the nucleus and how they contribute to organizing the genome, then moves to examine the direct roles of NPCs and their components in gene expression regulation in different organisms, and ends by describing the function of nuclear pores in the infection and genome integration of HIV, in DNA repair and telomere maintenance, and in the regulation of chromosome segregation and mitosis. This book provides an intellectual backdrop for anyone interested in understanding how the gatekeepers of the nucleus contribute to safeguarding the integrity and function of the eukaryotic genome. 248 pp. Englisch. N° de réf. du vendeur 9783319716121
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Vendeur : moluna, Greven, Allemagne
Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Clear description of the current knowledge in genome organizationExposes new concepts of the roles of nuclear pore complexes in genomic organization and genome protection/maintenanceA unique source of information on nuclear organization and. N° de réf. du vendeur 177690982
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Vendeur : Kennys Bookshop and Art Galleries Ltd., Galway, GY, Irlande
Etat : New. N° de réf. du vendeur V9783319716121
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Vendeur : Books Puddle, New York, NY, Etats-Unis
Etat : New. pp. VIII, 240 32 illus. in color. 1 Edition NO-PA16APR2015-KAP. N° de réf. du vendeur 26384556276
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Vendeur : buchversandmimpf2000, Emtmannsberg, BAYE, Allemagne
Buch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -¿Clear description of the current knowledge in genome organizationExposes new concepts of the roles of nuclear pore complexes in genomic organization and genome protection/maintenanceA unique source of information on nuclear organization and dynamics in one locationSpringer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 248 pp. Englisch. N° de réf. du vendeur 9783319716121
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Vendeur : AHA-BUCH GmbH, Einbeck, Allemagne
Buch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - The three-dimensional organization of the DNA inside the eukaryotic cell nucleus has emerged a critical regulator of genome integrity and function. Increasing evidence indicates that nuclear pore complexes (NPCs), the large protein channels that connect the nucleus to the cytoplasm, play a critical role in the establishment and maintenance of chromatin organization and in the regulation of gene activity. These findings, which oppose the traditional view of NPCs as channels with only one: the facilitation of nucleocytoplasmic molecule exchange, have completely transformed our understanding of these structures. This book describes our current knowledge of the role of NPCs in genome organization and gene expression regulation. It starts by providing an overview of the different compartments and structures of the nucleus and how they contribute to organizing the genome, then moves to examine the direct roles of NPCs and their components in gene expression regulation in different organisms, and ends by describing the function of nuclear pores in the infection and genome integration of HIV, in DNA repair and telomere maintenance, and in the regulation of chromosome segregation and mitosis. This book provides an intellectual backdrop for anyone interested in understanding how the gatekeepers of the nucleus contribute to safeguarding the integrity and function of the eukaryotic genome. N° de réf. du vendeur 9783319716121
Quantité disponible : 1 disponible(s)
Vendeur : Majestic Books, Hounslow, Royaume-Uni
Etat : New. Print on Demand pp. VIII, 240 32 illus. in color. N° de réf. du vendeur 379347755
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