Articles liés à Molecular Mechanisms of Notch Signaling
Molecular Mechanisms of Notch Signaling - Couverture rigide
Livre 368 sur 544: Advances in Experimental Medicine and Biology
Synopsis
This book describes the Notch signaling pathway with a focus on molecular mechanisms. The Notch signaling pathway is a seemingly simple pathway that does not involve any second messenger. Upon ligand binding two consecutive proteolytic cleavages of the NOTCH receptor release the Notch intracellular domain from the membrane. The Notch intracellular domain migrates into the nucleus and activates gene expression.
Recently, new technologies allowed us to better understand this pivotal signaling cascade and revealed new regulatory mechanisms. The different chapters cover many aspects of the Notch signaling focusing on the mechanisms governing the receptor/ligand interaction as well as on the downstream intracellular signaling events. Aspects of both canonical and non-canonical signaling are discussed and the function of Notch signaling in physiological and pathological contexts are elucidated.
This book is not only intended for experts but it should also be a usefulresource for young, sprouting scientists or interested scientists from other research areas, who may use this book as a stimulating starting point for further discoveries and developments.
Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.
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Molecular Mechanisms of Notch Signaling (eng)
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Molecular Mechanisms of Notch Signaling
Edité par
Springer International Publishing, 2018
ISBN 10 : 3319895117
ISBN 13 : 9783319895116
Neuf
Couverture rigide
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Gebunden. Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Provides the most recent overview of Notch signal transductionIs an in-depth introduction into molecular mechanisms of signal transduction exemplified by the Notch signaling pathwayCovers topics . N° de réf. du vendeur 218591176
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Molecular Mechanisms of Notch Signaling
Edité par
Springer International Publishing Aug 2018, 2018
ISBN 10 : 3319895117
ISBN 13 : 9783319895116
Neuf
Couverture rigide
Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne
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Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book describes the Notch signaling pathway with a focus on molecular mechanisms. The Notch signaling pathway is a seemingly simple pathway that does not involve any second messenger. Upon ligand binding two consecutive proteolytic cleavages of the NOTCH receptor release the Notch intracellular domain from the membrane. The Notch intracellular domain migrates into the nucleus and activates gene expression. Recently, new technologies allowed us to better understand this pivotal signaling cascade and revealed new regulatory mechanisms. The different chapters cover many aspects of the Notch signaling focusing on the mechanisms governing the receptor/ligand interaction as well as on the downstream intracellular signaling events. Aspects of both canonical and non-canonical signaling are discussed and the function of Notch signaling in physiological and pathological contexts are elucidated. This book is not only intended for experts but it should also be a useful resource for young, sprouting scientists or interested scientists from other research areas, who may use this book as a stimulating starting point for further discoveries and developments. 428 pp. Englisch. N° de réf. du vendeur 9783319895116
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Molecular Mechanisms of Notch Signaling
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Springer, Palgrave Macmillan Aug 2018, 2018
ISBN 10 : 3319895117
ISBN 13 : 9783319895116
Neuf
Couverture rigide
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Buch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -This book describes the Notch signaling pathway with a focus on molecular mechanisms. The Notch signaling pathway is a seemingly simple pathway that does not involve any second messenger. Upon ligand binding two consecutive proteolytic cleavages of the NOTCH receptor release the Notch intracellular domain from the membrane. The Notch intracellular domain migrates into the nucleus and activates gene expression.Recently, new technologies allowed us to better understand this pivotal signaling cascade and revealed new regulatory mechanisms. The different chapters cover many aspects of the Notch signaling focusing on the mechanisms governing the receptor/ligand interaction as well as on the downstream intracellular signaling events. Aspects of both canonical and non-canonical signaling are discussed and the function of Notch signaling in physiological and pathological contexts are elucidated.This book is not only intended for experts but it should also be a usefulresource for young, sprouting scientists or interested scientists from other research areas, who may use this book as a stimulating starting point for further discoveries and developments.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 428 pp. Englisch. N° de réf. du vendeur 9783319895116
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Molecular Mechanisms of Notch Signaling (Advances in Experimental Medicine and Biology (1066))
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Molecular Mechanisms of Notch Signaling (Advances in Experimental Medicine and Biology (1066))
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Molecular Mechanisms of Notch Signaling
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Buch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - This book describes the Notch signaling pathway with a focus on molecular mechanisms. The Notch signaling pathway is a seemingly simple pathway that does not involve any second messenger. Upon ligand binding two consecutive proteolytic cleavages of the NOTCH receptor release the Notch intracellular domain from the membrane. The Notch intracellular domain migrates into the nucleus and activates gene expression. Recently, new technologies allowed us to better understand this pivotal signaling cascade and revealed new regulatory mechanisms. The different chapters cover many aspects of the Notch signaling focusing on the mechanisms governing the receptor/ligand interaction as well as on the downstream intracellular signaling events. Aspects of both canonical and non-canonical signaling are discussed and the function of Notch signaling in physiological and pathological contexts are elucidated. This book is not only intended for experts but it should also be a usefulresource for young, sprouting scientists or interested scientists from other research areas, who may use this book as a stimulating starting point for further discoveries and developments. N° de réf. du vendeur 9783319895116
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Molecular Mechanisms of Notch Signaling (Advances in Experimental Medicine and Biology, 1066)
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