Fast Dissolving Tablets - Couverture souple

Maithani, Richa; Singh, Ranjit; Bansal, Parveen

 
9783330038608: Fast Dissolving Tablets
Couverture souple
ISBN 10 : 3330038608 ISBN 13 : 9783330038608
Editeur : LAP LAMBERT Academic Publishing, 2017

Synopsis

Difficulty in swallowing is common among all age groups, especially in elderly and pediatrics. Fast dissolving tablets constitute an innovative dosage forms that overcome the problems of swallowing and provide a quick onset of action. Fast-dissolving drug delivery system, in most cases, is a tablet that dissolves or disintegrates in the oral cavity without the need of water or chewing. Fast-dissolving drug delivery system must include substances to mask the taste of the active ingredient. This masked active ingredient is then swallowed by the patient’s saliva along with the soluble and insoluble excipients. Loratadine is antihistaminic drugs which is H1receptor blocker used in the treatment of hay fever and other dermatalogical diseases. In the present study, loratadine fast dissolving tablets were prepared by solid dispersion and using croscarmellose sodium, sodium starch glycolate and polyplasdone XL as super disintegrants. The preformulation study indicated that it is suitable for direct compression. The drug contents of all the tablets were found to be uniform with low standard deviation, indicating efficient mixing and showed quick disintegration and higher dissolution.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Difficulty in swallowing is common among all age groups, especially in elderly and pediatrics. Fast dissolving tablets constitute an innovative dosage forms that overcome the problems of swallowing and provide a quick onset of action. Fast-dissolving drug delivery system, in most cases, is a tablet that dissolves or disintegrates in the oral cavity without the need of water or chewing. Fast-dissolving drug delivery system must include substances to mask the taste of the active ingredient. This masked active ingredient is then swallowed by the patient’s saliva along with the soluble and insoluble excipients. Loratadine is antihistaminic drugs which is H1receptor blocker used in the treatment of hay fever and other dermatalogical diseases. In the present study, loratadine fast dissolving tablets were prepared by solid dispersion and using croscarmellose sodium, sodium starch glycolate and polyplasdone XL as super disintegrants. The preformulation study indicated that it is suitable for direct compression. The drug contents of all the tablets were found to be uniform with low standard deviation, indicating efficient mixing and showed quick disintegration and higher dissolution.

Biographie de l'auteur

Richa Maithani did Master of Pharmacy (Pharmaceutics) in 2011 from Shobhit University, Meerut. She is pursuing PhD in Pharmaceutical Sciences as Research Scholar. She has published number of research and review articles in Journals national and international of repute.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2017
Langue
anglais
ISBN 10 
3330038608
ISBN 13 
9783330038608
Reliure
Broché
Nombre de pages
84
Coordonnées du fabricant
non disponible
Personne responsable
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