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QSAR Study of Potent Gsk-3β Inhibitor for Type II Diabetes: Chemometric analysis based methods for new therapeutic application - Couverture souple

Mishra, Pooja; Kesar, Seema

 
9783330040434: QSAR Study of Potent Gsk-3β Inhibitor for Type II Diabetes: Chemometric analysis based methods for new therapeutic application
Couverture souple
ISBN 10 : 3330040432 ISBN 13 : 9783330040434
Editeur : LAP LAMBERT Academic Publishing, 2017

Synopsis

This is a best book for analyzing 2D QSAR technique for determining the potent GSK-3beta inhibitor against diabetes.Computer-aided drug design is a branch of medicinal/computational chemistry and is of great interest now a day. Computer-aided design of chemical compounds with controlled properties is generally performed using computer-aided design systems.Its becoming increasingly involved in understanding the differences between potent molecules and drug candidates (ADMET-absorption, distribution, metabolism, excretion and toxicity) this is already fueling a rise in impact and expectations for CADD. The use of quantitative structure-activity relationships (QSAR) has become increasingly helpful in understanding many aspects of chemical-biological interactions in drug and other scientific research. In the present effort, we exaggerate our pursuit of being establishing the relationship between the various physiochemical parameters and anti-diabetic activity of 3-aryl- 4-(arylhydrazono)-1H pyrazol-5-ones derivatives by using classical quantitative structure– activity relationship (QSAR) descriptors and similarity indices.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

This is a best book for analyzing 2D QSAR technique for determining the potent GSK-3beta inhibitor against diabetes.Computer-aided drug design is a branch of medicinal/computational chemistry and is of great interest now a day. Computer-aided design of chemical compounds with controlled properties is generally performed using computer-aided design systems.Its becoming increasingly involved in understanding the differences between potent molecules and drug candidates (ADMET-absorption, distribution, metabolism, excretion and toxicity) this is already fueling a rise in impact and expectations for CADD. The use of quantitative structure-activity relationships (QSAR) has become increasingly helpful in understanding many aspects of chemical-biological interactions in drug and other scientific research. In the present effort, we exaggerate our pursuit of being establishing the relationship between the various physiochemical parameters and anti-diabetic activity of 3-aryl- 4-(arylhydrazono)-1H pyrazol-5-ones derivatives by using classical quantitative structure– activity relationship (QSAR) descriptors and similarity indices.

Biographie de l'auteur

Dr Pooja Mishra was born in Khalilabad & received her bachelor's as well as master degree in pharmacy from G.B.T.U & Banasthali Uni. respectively. In 2013, she joined as research fellow at Banasthali Uni, India. She is an active researcher in area of computational & synthetic chemistry for designing a bioactive molecules having multitarget approach

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2017
Langue
anglais
ISBN 10 
3330040432
ISBN 13 
9783330040434
Reliure
Broché
Nombre de pages
64
Coordonnées du fabricant
non disponible
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