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Development of Isoniazid Loaded Silk Fibroin Microsphere: Development of Microsphere for Antitubercular Drug - Couverture souple

Singh, Narinder; Gautam, Surya Prakash; Kaur, Rajinderpal

 
9783330057678: Development of Isoniazid Loaded Silk Fibroin Microsphere: Development of Microsphere for Antitubercular Drug
Couverture souple
ISBN 10 : 333005767X ISBN 13 : 9783330057678
Editeur : LAP LAMBERT Academic Publishing, 2017

Synopsis

Current experimental investigation is dedicated to prepare microspheres with small size and good Sphericity by Phase Separation method using Isoniazid (INH) as model drug. Silk fibroin has unique intrinsic qualities like biodegradability, biocompatibility or release properties and their tunable drug loading capacity. The delivery loading proficiency of the drug molecules in silk spheres be contingent on their charge and hydrophobicity or subsequent in altered drug release profile. In the present work Isoniazid loaded silk fibroin microsphere was prepared by using phase Separation method. Microsphere was evaluated by Ultraviolet-visible spectroscopy, Fourier Transform Infrared spectroscopy, Entrapment efficiency, Scanning electron microscopy Studies. Scanning electron microscopy studies revealed that Isoniazid Loaded Silk Fibroin Microspheres were spherical. Experimental report disclosed a new aqueous based formulation method for silk spheres with controllable shape or size and sphere. Isoniazid loaded silk microspheres may act as ideal nanoformulation with elaborated studies.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Current experimental investigation is dedicated to prepare microspheres with small size and good Sphericity by Phase Separation method using Isoniazid (INH) as model drug. Silk fibroin has unique intrinsic qualities like biodegradability, biocompatibility or release properties and their tunable drug loading capacity. The delivery loading proficiency of the drug molecules in silk spheres be contingent on their charge and hydrophobicity or subsequent in altered drug release profile. In the present work Isoniazid loaded silk fibroin microsphere was prepared by using phase Separation method. Microsphere was evaluated by Ultraviolet-visible spectroscopy, Fourier Transform Infrared spectroscopy, Entrapment efficiency, Scanning electron microscopy Studies. Scanning electron microscopy studies revealed that Isoniazid Loaded Silk Fibroin Microspheres were spherical. Experimental report disclosed a new aqueous based formulation method for silk spheres with controllable shape or size and sphere. Isoniazid loaded silk microspheres may act as ideal nanoformulation with elaborated studies.

Biographie de l'auteur

Narinder Singh (M.Pharma) (Pharmaceutics) from CT Institute of Pharmaceutical Sciences, Jalandhar, Punjab with first division & (B.Pharma) from Rayat-Bahra Institute of Pharmacy, Hoshiarpur, Punjab. Author has presence in the pharmaceutics research.Have authored research/review publications.Author has grateful to Parents & Dr. Surya Prakash Gautam.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2017
Langue
anglais
ISBN 10 
333005767X
ISBN 13 
9783330057678
Reliure
Broché
Nombre de pages
92
Coordonnées du fabricant
non disponible
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