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Analysis of Mesenchymal Stromal Cell Ageing: Based on Microarray Gene Expression Profile - Couverture souple

Naithani, Jyoti

 
9783330058286: Analysis of Mesenchymal Stromal Cell Ageing: Based on Microarray Gene Expression Profile
Couverture souple
ISBN 10 : 3330058285 ISBN 13 : 9783330058286
Editeur : LAP LAMBERT Academic Publishing, 2017

Synopsis

Mesenchymal stem cells are of great therapeutic potential because of their ability to self-renew and differentiate into multiple tissues. Ageing in these cells is accompanied by a progressive decline in its function, resulting in less effective tissue homeostasis and repair. The main aim of our work is to find a set of key genes which have significant roles in ageing of mesenchymal stromal cells and also to find out how they are regulating other genes or pathways. With the invention of DNA microarray technology, it is now possible to look globally at gene expression across the genome. By studying gene expression profile we can know the interactions between genes and how this ultimately impacts on the ageing of mesenchymal stromal cells. Mesenchymal stem cells are in the center of attention of many investigators due to easy isolation from many tissues. MSC capability to differentiate into many cell types makes them a starting point of many new therapies, especially in tissue engineering.

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Présentation de l'éditeur

Mesenchymal stem cells are of great therapeutic potential because of their ability to self-renew and differentiate into multiple tissues. Ageing in these cells is accompanied by a progressive decline in its function, resulting in less effective tissue homeostasis and repair. The main aim of our work is to find a set of key genes which have significant roles in ageing of mesenchymal stromal cells and also to find out how they are regulating other genes or pathways. With the invention of DNA microarray technology, it is now possible to look globally at gene expression across the genome. By studying gene expression profile we can know the interactions between genes and how this ultimately impacts on the ageing of mesenchymal stromal cells. Mesenchymal stem cells are in the center of attention of many investigators due to easy isolation from many tissues. MSC capability to differentiate into many cell types makes them a starting point of many new therapies, especially in tissue engineering.

Biographie de l'auteur

Jyoti Naithani, MSc: studied Medical Biotechnology at Maharshi Dayanand University. Working as Microbiologist at Cu-V-Kar Genetic Medicines.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2017
Langue
anglais
ISBN 10 
3330058285
ISBN 13 
9783330058286
Reliure
Broché
Nombre de pages
56
Coordonnées du fabricant
non disponible
Personne responsable
non disponible