Effect of Arsenic on T cells in Rheumatoid Arthritis: Arsenic in Rheumatoid Arthritis - Couverture souple

Chaudhary, Archana; Haque, Rizwanul

 
9783330067691: Effect of Arsenic on T cells in Rheumatoid Arthritis: Arsenic in Rheumatoid Arthritis
Couverture souple
ISBN 10 : 3330067691 ISBN 13 : 9783330067691
Editeur : LAP LAMBERT Academic Publishing, 2017

Synopsis

Rheumatoid arthritis (RA), as a serious RA complication took the life of many people’s worldwide. As of now, doctors do not know what causes the disease, although it is estimated that it likely brought on by a combination of factors including genetics and environmental influences such as arsenic(As) exposure. Arsenic(As) is a paradoxical human carcinogen affecting millions of people around the world. At present, people in more than 35 countries across the globe are affected by drinking arsenic-contaminated ground water. Because there isn’t one specific cause of the disease, there is also no known cure for rheumatoid arthritis. The primary function of Regulatory T cells (Treg ) was originally defined as prevention of autoimmune diseases such as Rheumatoid arthritis by maintaining self-tolerance. Recent report evidences that arsenic affect Treg cells population. So the authors wants to emphasise in this book that, how arsenic modulate FoxP3 expression which is a master regulator of Treg cells in Rheumatoid arthritis .This study for the first time suggests that arsenic modulate the Foxp3 gene expression.

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Présentation de l'éditeur

Rheumatoid arthritis (RA), as a serious RA complication took the life of many people’s worldwide. As of now, doctors do not know what causes the disease, although it is estimated that it likely brought on by a combination of factors including genetics and environmental influences such as arsenic(As) exposure. Arsenic(As) is a paradoxical human carcinogen affecting millions of people around the world. At present, people in more than 35 countries across the globe are affected by drinking arsenic-contaminated ground water. Because there isn’t one specific cause of the disease, there is also no known cure for rheumatoid arthritis. The primary function of Regulatory T cells (Treg ) was originally defined as prevention of autoimmune diseases such as Rheumatoid arthritis by maintaining self-tolerance. Recent report evidences that arsenic affect Treg cells population. So the authors wants to emphasise in this book that, how arsenic modulate FoxP3 expression which is a master regulator of Treg cells in Rheumatoid arthritis .This study for the first time suggests that arsenic modulate the Foxp3 gene expression.

Biographie de l'auteur

Archana ChaudharyPhd ScholarCentral University of South Bihar . Area of interest· Wants to overcome arsenic menace from the field of immunology by modulating both the function and number of Treg cells .· M. Sc. (Biotechnology).Academic achievements· Qualified CSIR NET-Dec-2016 & GATE in Lifescience.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2017
Langue
anglais
ISBN 10 
3330067691
ISBN 13 
9783330067691
Reliure
Broché
Nombre de pages
56
Coordonnées du fabricant
non disponible
Personne responsable
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