Articles liés à Quantitative Bioanalysis of Anticancer Drugs by LC-MS/MS:...

Quantitative Bioanalysis of Anticancer Drugs by LC-MS/MS: Analysis of Anticancer Drugs - Couverture souple

Bharwad, Kirtikumar D.; Shrivastav, Pranav; Shah, Priyanka

 
9783330080515: Quantitative Bioanalysis of Anticancer Drugs by LC-MS/MS: Analysis of Anticancer Drugs
Couverture souple
ISBN 10 : 3330080515 ISBN 13 : 9783330080515
Editeur : LAP LAMBERT Academic Publishing, 2017

Synopsis

Monitoring of anticancer drugs in biological fluids and tissues is important during pre-clinical and clinical use. Traditionally, liquid chromatography (LC) in combination with ultraviolet, fluorescence, or electrochemical detection is employed for this purpose. The successful hyphenation of LC and mass spectrometry (MS), however, has dramatically changed scope of analysis. MS detection provides better sensitivity and selectivity than UV detection and, in addition, is applicable to a significantly larger group of compounds than fluorescence or electrochemical detection. As new drugs continuously emerge in the market, this methodology has now become the method of choice in quantitative bioanalysis, particularly when many samples have to be analyzed in a short time period. The need to analyze anticancer drugs and their metabolites with prompt turnaround times has stimulated even more rapid approaches to analysis, using robotic based purification methodology and short LC chromatographic run times.

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À propos de l'auteur

Mr. Kirtikumar D. Bharwad is a research scholar at the Department of Chemistry, Gujarat University (GU). He did his Bachelors, Masters and MPhil in Chemistry from the same University, and will be pursuing for doctoral studies at GU. He was also elected as a senate member of Akhil Bharatiya Vidyarthi Parishad (ABVP) at GU in the year of 2015.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2017
Langue
anglais
ISBN 10 
3330080515
ISBN 13 
9783330080515
Reliure
Broché
Nombre de pages
84
Coordonnées du fabricant
non disponible
Personne responsable
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