Biochemistry of Signal Transduction and Regulation - Couverture rigide

Krauss, Gerhard

Couverture rigide

ISBN 10 : 3527297715 ISBN 13 : 9783527297719

Editeur : Wiley-VCH Verlag GmbH, 1999

Synopsis

Intracellular signal transduction, regulation of cell activities, and tumor formation - how do they work? This question is of central importance in biochemical research. The 1990s have seen great progress in the understanding of the molecular basis of biological signal transduction, and many facts are known by every medicinal chemist, biochemist, and biologist. This book relates the observed biological phenomena to the underlying biological processes. The topics range from function, structure and integral construction of signalling pathways, including a detailed description of the various types of carriers, to regulation of the cell cycle, and the role of ion channels in signal transduction. Special emphasis is placed on oncogenesis and tumour suppressants. A comprehensive bibliography including review articles provides access to the primary literature on the subject.

A propos du livre

Présentation de l'éditeur

Now the updated second edition of this bestselling title is available as softcover!

Intracellular signal transduction, regulation of cellular activities, tumor formation, apoptosis – how do they work? These questions have become a central topic in Biology and Biological Chemistry. The importance of this field is mirrored in the 1999 Nobel prize for Physiology that went to G. Blobel for his findings in protein transport regulation.

Over the last decade there has been great progress in the understanding of the molecular basis of signal transduction, and many facts are now basic knowledge for every medicinal chemist, biochemist, and biologist. Since an integral description of cellular regulation and signal transduction is scarcely covered in textbooks, this book fills a real gap. Starting from the principles of gene regulation and regulation of enzyme activity, the topics of this book cover function, structure, and integral construction of signalling pathways plus a detailed description of the various types of carriers such as second messengers, protein kinases, and transmembrane receptors. Central cellular processes like cell cycle regulation, oncogenesis and apoptosis are discussed in light of the properties of the signalling molecules involved. With didactic skill and clarity the author relates the observed biological phenomena to the underlying biochemical processes.
This book is actually two books: Regulation and Signal Transduction.

Revue de presse

"The clear and didactic presentation makes it a textbook very useful for students and researchers not familiar with all aspects of cell regulation." (Biochemie, No. 83, 2001)

"...very comprehensive...useful for teachers, researchers and students..." (Biochemie, Vol.84, No.4, 2002)

"...describes the structural and biochemical properties of signaling molecules and their regulation..." (SciTech Book News, Vol. 26, No. 2, June 2002)

"...should provide a useful guide to undergraduate students..."(Applied Organometallic Chemistry, November 2002)

"The clear and didactic presentation makes it a textbook very useful for students and researchers not familiar with all aspects of cell regulation." (Biochemie, No. 83, 2001)

"...very comprehensive...useful for teachers, researchers and students..." (Biochemie, Vol.84, No.4, 2002)

"...describes the structural and biochemical properties of signaling molecules and their regulation..." (SciTech Book News, Vol. 26, No. 2, June 2002)

"...should provide a useful guide to undergraduate students..."(Applied Organometallic Chemistry, November 2002)

Détails de l'édition

• Éditeur: Wiley-VCH Verlag GmbH
• Date d'édition: 1999
• Langue: anglais
• ISBN 10: 3527297715
• ISBN 13: 9783527297719
• Reliure: Relié
• Nombre de pages: 528
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible