Virtual Screening for Bioactive Molecules - Couverture rigide

 
9783527301539: Virtual Screening for Bioactive Molecules
Couverture rigide
ISBN 10 : 3527301534 ISBN 13 : 9783527301539
Editeur : Wiley-VCH Verlag GmbH, 2000

Synopsis

Recent progress in high-throughput screening, combinatorial chemistry and molecular biology has radically changed the approach to drug discovery in the pharmaceutical industry. New challenges in synthesis result in new analytical methods. At present, typically 100,000 to one million molecules have to be tested within a short period and, therefore, highly effective screening methods are necessary for today's researchers - preparing and characterizing one compound after another belongs to the past. Intelligent, computer-based search agents are needed and "virtual screening" provides solutions to many problems. Such screening comprises innovative computational techniques designed to turn raw data into valuable chemical information and to assist in extracting the relevant molecular features. This handbook is unique in bringing together the various efforts in the field of virtual screening to provide the necessary methodological framework for more effective research. Leading experts give a thorough introduction to the state of the art along with a critical assessment of both successful applications and drawbacks. The information collated here will be indispensable for experienced scientists, as well as novices, working in medicinal chemistry and related disciplines.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Recent progress in high–throughput screening, combinatorial chemistry and molecular biology has radically changed the approach to drug discovery in the pharmaceutical industry. New challenges in synthesis result in new analytical methods. At present, typically 100,000 to one million molecules have to be tested within a short period and, therefore, highly effective screening methods are necessary for today′s researchers – preparing and characterizing one compound after another belongs to the past. Intelligent, computer–based search agents are needed and "virtual screening" provides solutions to many problems. Such screening comprises innovative computational techniques designed to turn raw data into valuable chemical information and to assist in extracting the relevant molecular features.

This handbook is unique in bringing together the various efforts in the field of virtual screening to provide the necessary methodological framework for more effective research. Leading experts give a thorough introduction to the state of the art along with a critical assessment of both successful applications and drawbacks. The information collated here will be indispensable for experienced scientists, as well as novices, working in medicinal chemistry and related disciplines.

Revue de presse

"There is little in the book that can be criticised" (Chemistry & Industry, 19 November, 2001)

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
Wiley-VCH Verlag GmbH
Date d'édition
2000
Langue
anglais
ISBN 10 
3527301534
ISBN 13 
9783527301539
Reliure
Relié
Nombre de pages
325
Éditeur
Bohm Hans-Joachim, Schneider Gisbert, Kubinyi Hugo, Mannhold Raimund, Timmerman Hendrik
Coordonnées du fabricant
non disponible
Personne responsable
non disponible