Prodrugs and Targeted Delivery: Towards Better ADME Properties - Couverture rigide

Couverture rigide

ISBN 10 : 3527326030 ISBN 13 : 9783527326037

Editeur : Blackwell Verlag GmbH, 2010

Synopsis

This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning at the early stages of the development process, as well as discussing organ- and site-selective prodrugs.
Every company employing medicinal chemists will be interested in this practice-oriented overview of a key strategy in modern drug discovery and development.

A propos du livre

À propos de l'auteur

Jarkko Rautio is professor of pharmaceutical chemistry and head of the multidisciplinary Pharmaceutical and Medicinal Chemistry (PMC) research group at the School of Pharmacy, University of Eastern Finland (formerly University of Kuopio), where he received his PhD in pharmaceutical chemistry in 2000. He subsequently carried out his postdoctoral studies at the University of Maryland, Baltimore, USA, and was a visiting scientist at GlaxoSmithKline, North Carolina, while also co-founding the American Association of Pharmaceutical Scientists (AAPS) Prodrug Focus Group in 2005. Professor Rautio's research focuses on chemistry-based methods, especially prodrugs, to overcome the liabilities of drugs.

Détails de l'édition

• Éditeur: Blackwell Verlag GmbH
• Date d'édition: 2010
• Langue: anglais
• ISBN 10: 3527326030
• ISBN 13: 9783527326037
• Reliure: Relié
• Nombre de pages: 520
• Éditeur: Rautio Jarkko
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible