Model Systems in Aging - Couverture rigide

Couverture rigide

ISBN 10 : 3540024905 ISBN 13 : 9783540024903

Editeur : Springer-Verlag Berlin and Heidelberg GmbH & Co. K, 2003

Synopsis

Aging is the progressive decline in biological functions over time. This decline targets macromolecules, cells, tissues and, as a consequence, whole organisms. Despite considerable progress in the development of testable hypothesis concerning aging in an evolutionary context, a unifying theory of the molecular/physiological mechanistic causes of aging has not been reached. In fact, is it not clear to what extent aging is a programmed or stochastic process.

This book takes the reader from unicellular bacterial deterioration via senescence in fungi and worms to aging in rodents and humans, allowing a comparative view on similarities and differences in different genetic model systems. The different model systems are scrutinized in the light of contemporary aging hypothesis, such as the free radical and genomic instability theories.

Détails de l'édition

• Éditeur: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
• Date d'édition: 2003
• Langue: anglais
• ISBN 10: 3540024905
• ISBN 13: 9783540024903
• Reliure: Relié
• Nombre de pages: 316
• Éditeur: Nyström Thomas, Osiewacz Heinz D.
• Coordonnées du fabricant: ProductSafety@springernature.com; ProductSafety@springernature.com; ; Poststr. 9; Darmstadt; 64293; Allemagne