The Ontogenesis of Cortical Circuitry: The Spatial Distribu- Tion Of Synapses In Somesthetic Cortex Of Newborn Dog. (Advances In Anatomy, Embryology And Cell Biology) - Couverture souple

Molliver, M. E.

Couverture souple

ISBN 10 : 3540047972 ISBN 13 : 9783540047971

Editeur : Springer, 1970

Synopsis

The ontogenesis of cortical circuitry is the subject of the investigation reported in this paper!. Strategie elements of cortical circuitry are synaptic contacts: sites of neuronal interaction. If we first determine the location of early formed synap- ses, we may then seek the pre-and postsynaptic elements, that is, the structures which meet and interact at each synaptic junction. The dynamic aspects of cortical development cannot be studied directly: neuronal growth cannot be observed in an intact brain. The pattern of develop- ment can be approached only by the analysis of static properties at multiple ages. We have selected the newborn dog as a starting point for these studies. Our observations have been restricted to a small portion of primary somesthetic cor- tex. This region was selected because, in mature cortex, its input and physiologie properties are relatively weIl known. It is particularly advantageous to study a primary sensory projection area because its morphologie development can be di- rectly related to its functional development. (A related investigation of the onto- genesis of electrical activity in somesthetic cortex of the dog will be reported separately). A selective review of the literature is necessary in order to place this work in the context of a few relevant phenomena of cortical development.

Détails de l'édition

• Éditeur: Springer
• Date d'édition: 1970
• Langue: anglais
• ISBN 10: 3540047972
• ISBN 13: 9783540047971
• Reliure: Broché
• Nombre de pages: 60
• Coordonnées du fabricant: ProductSafety@springernature.com; ProductSafety@springernature.com; ; Poststr. 9; Darmstadt; 64293; Allemagne