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Steric Fit in Quantitative Structure-Activity Relations (Lecture Notes in Chemistry) - Couverture souple
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Although the importance of steric fit for receptor-effector 1 interactions was recognized since Emil Fischer proposed his "lock and key" theory, the whole area of steric properties is still in a very 2-4 early stage of development. We have a fairly good idea about el- tronic and hydrophobic parameters, but it is not easy to describe ste- ric shapes of molecules without a large number of data. There are se- veral cases of good QSAR's developed for rather large series of mole- 5 cules without steric parameters - for example see papers by Hansch, 6 or Franke, but the state of steric parameters is nevertheless one of the most important drawbacks, especially concerning the ability of en- compassing, within a single QSAR, molecules of different shapes and stereoisomers. From today's steric parameters, one may mention the 7 Taft parameters E ' which gave good results in organic chemistry, the S 8 10 ra th er cum b ersome way 0 f measurIng - s h ape d'ff I ere h ces 0 f Amoore - and, 11 12 AllInger, and the L, B -B parameters of Verloop 1 4 The work described here consists of two types of approaches to the steric fit problem. The first approach consists of developing new parameters to describe different characteristics of the molecular shape (i. e., branching, bulkiness); this is done by means of topological in- dices.
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Steric fit in quantitative structure-activity relations
Edité par
Springer-Verlag, 1980
ISBN 10 : 3540097554
ISBN 13 : 9783540097556
Ancien ou d'occasion
Couverture souple
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Vendeur : Cotswold Internet Books, Cheltenham, Royaume-Uni
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Etat : Used - Good. Good paperback. 1st edition. Lecture Notes in Chemistry 15. Bodleian Library stamps & notation on cover & title page; small red ink stain on spine; slight wear to spine joints. N° de réf. du vendeur BOOKS232901I
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Steric Fit in Quantitative Structure-Activity Relations
Edité par
Springer Berlin Heidelberg, 1980
ISBN 10 : 3540097554
ISBN 13 : 9783540097556
Neuf
Couverture souple
Vendeur : moluna, Greven, Allemagne
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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Detailed Contents.- 1 Introduction.- 2 Steric and other Structural Parameters for QSAR.- 2.1 Correlational Equations and Predictor Variables.- 2.2 Steric Parameters.- 2.2.1 Taft Type Steric Parameters: ES, ESc, ESo, ESe and v.- 2.2.2 Amoore Type Steric Para. N° de réf. du vendeur 4880625
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Steric Fit in Quantitative Structure-Activity Relations
Edité par
Springer Berlin Heidelberg, 1980
ISBN 10 : 3540097554
ISBN 13 : 9783540097556
Neuf
Taschenbuch
Vendeur : AHA-BUCH GmbH, Einbeck, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - Although the importance of steric fit for receptor-effector 1 interactions was recognized since Emil Fischer proposed his 'lock and key' theory, the whole area of steric properties is still in a very 2-4 early stage of development. We have a fairly good idea about el- tronic and hydrophobic parameters, but it is not easy to describe ste ric shapes of molecules without a large number of data. There are se veral cases of good QSAR's developed for rather large series of mole- 5 cules without steric parameters - for example see papers by Hansch , 6 or Franke , but the state of steric parameters is nevertheless one of the most important drawbacks, especially concerning the ability of en compassing, within a single QSAR, molecules of different shapes and stereoisomers. From today's steric parameters, one may mention the 7 Taft parameters E ' which gave good results in organic chemistry, the S 8 10 ra th er cum b ersome way 0 f measurIng s h ape d'ff I ere h ces 0 f Amoore - and , 11 12 AllInger ,and the L, B -B parameters of Verloop 1 4 The work described here consists of two types of approaches to the steric fit problem. The first approach consists of developing new parameters to describe different characteristics of the molecular shape (i. e. , branching, bulkiness); this is done by means of topological in dices. N° de réf. du vendeur 9783540097556
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Steric Fit in Quantitative Structure-Activity Relations (Lecture Notes in Chemistry, 15)
Vendeur : Ria Christie Collections, Uxbridge, Royaume-Uni
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Etat : New. In. N° de réf. du vendeur ria9783540097556_new
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Steric Fit in Quantitative Structure-Activity Relations
Vendeur : Chiron Media, Wallingford, Royaume-Uni
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PF. Etat : New. N° de réf. du vendeur 6666-IUK-9783540097556
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Steric Fit in Quantitative Structure-Activity Relations
Edité par
Springer Berlin Heidelberg, Springer Berlin Heidelberg Apr 1980, 1980
ISBN 10 : 3540097554
ISBN 13 : 9783540097556
Neuf
Taschenbuch
Vendeur : buchversandmimpf2000, Emtmannsberg, BAYE, Allemagne
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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Although the importance of steric fit for receptor-effector 1 interactions was recognized since Emil Fischer proposed his 'lock and key' theory, the whole area of steric properties is still in a very 2-4 early stage of development. We have a fairly good idea about el- tronic and hydrophobic parameters, but it is not easy to describe ste ric shapes of molecules without a large number of data. There are se veral cases of good QSAR's developed for rather large series of mole- 5 cules without steric parameters - for example see papers by Hansch , 6 or Franke , but the state of steric parameters is nevertheless one of the most important drawbacks, especially concerning the ability of en compassing, within a single QSAR, molecules of different shapes and stereoisomers. From today's steric parameters, one may mention the 7 Taft parameters E ' which gave good results in organic chemistry, the S 8 10 ra th er cum b ersome way 0 f measurIng s h ape d'ff I ere h ces 0 f Amoore - and , 11 12 AllInger ,and the L, B -B parameters of Verloop 1 4 The work described here consists of two types of approaches to the steric fit problem. The first approach consists of developing new parameters to describe different characteristics of the molecular shape (i. e. , branching, bulkiness); this is done by means of topological in dices.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 196 pp. Englisch. N° de réf. du vendeur 9783540097556
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Steric Fit in Quantitative Structure-Activity Relations (Lecture Notes in Chemistry)
Vendeur : Revaluation Books, Exeter, Royaume-Uni
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Paperback. Etat : Brand New. 1st edition. 196 pages. 9.61x6.69x0.45 inches. In Stock. N° de réf. du vendeur x-3540097554
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Steric Fit in Quantitative Structure-Activity Relations
Edité par
Springer Berlin Heidelberg Apr 1980, 1980
ISBN 10 : 3540097554
ISBN 13 : 9783540097556
Neuf
Taschenbuch
Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Although the importance of steric fit for receptor-effector 1 interactions was recognized since Emil Fischer proposed his 'lock and key' theory, the whole area of steric properties is still in a very 2-4 early stage of development. We have a fairly good idea about el- tronic and hydrophobic parameters, but it is not easy to describe ste ric shapes of molecules without a large number of data. There are se veral cases of good QSAR's developed for rather large series of mole- 5 cules without steric parameters - for example see papers by Hansch , 6 or Franke , but the state of steric parameters is nevertheless one of the most important drawbacks, especially concerning the ability of en compassing, within a single QSAR, molecules of different shapes and stereoisomers. From today's steric parameters, one may mention the 7 Taft parameters E ' which gave good results in organic chemistry, the S 8 10 ra th er cum b ersome way 0 f measurIng s h ape d'ff I ere h ces 0 f Amoore - and , 11 12 AllInger ,and the L, B -B parameters of Verloop 1 4 The work described here consists of two types of approaches to the steric fit problem. The first approach consists of developing new parameters to describe different characteristics of the molecular shape (i. e. , branching, bulkiness); this is done by means of topological in dices. 196 pp. Englisch. N° de réf. du vendeur 9783540097556
Quantité disponible : 2 disponible(s)
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Steric Fit in Quantitative Structure-Activity Relations (Lecture Notes in Chemistry, 15)
Edité par
Springer, 1980
ISBN 10 : 3540097554
ISBN 13 : 9783540097556
Ancien ou d'occasion
Paperback
Vendeur : Mispah books, Redhill, SURRE, Royaume-Uni
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Paperback. Etat : Very Good. Very Good. book. N° de réf. du vendeur ERICA80035400975546
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