Origins of Depression: Report of the Dahlem Workshop on the Origins of Depression: Current Concepts and Approaches Berlin 1982, Oct.31 - Nov. 5 - Couverture rigide

Checkley, S. A.

Couverture rigide

ISBN 10 : 3540124519 ISBN 13 : 9783540124511

Editeur : Springer-Verlag Berlin and Heidelberg GmbH & Co. K, 1983

Synopsis

3 and a fraction mayor may not respond to treatment. On the behavioral level, animal research shows that a variety of experimental conditions can induce de- pression. The same is true in the field of treatment, where pharmacologically highly different drugs can equally alleviate depression in animals and hu- mans. The question as to whether this is due to a heterogeneity of depressive subjects based on different pathogenetic mechanisms is open to discussion. We can look for common features of all possible causal factors in the hope of finding a single basic mechanism. Many divergent findings may also be ex- plained as peripheral changes of a highly complicated dynamic system. In the field of psychopharmacology, a circular reasoning has become evident in the sense that originally the clinical antidepressive response was founded on empirical grounds only. In a second step, an attempt was made to characterize some clinically active compounds pharmacologically, and in a third, further compounds were developed based on aspects of the pharmaco- logical profiles. Moreover, the post hoc development of a pharmacological screening method has the serious disadvantage of delaying breakthroughs into new fields.

Détails de l'édition

• Éditeur: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
• Date d'édition: 1983
• Langue: anglais
• ISBN 10: 3540124519
• ISBN 13: 9783540124511
• Reliure: Relié
• Nombre de pages: 484
• Éditeur: Angst J., Carlsson A., Carroll B. J., Helmchen Hanfried, Herz A.
• Coordonnées du fabricant: non disponible
• Personne responsable: CMN Printpool Inh. Mathis Neumann; https://www.also.com/ec/cms5/en_6000/6000/index.jsp; ; Friedrich-Karl-Str. 9; 0; Hamburg; 22391; Allemagne