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Synopsis
The search for ways to overcome tumour radioresistance is a major problem of experimental and clinical radiation oncology. The diffi- culties involved in the attempts to solve this problem are a matter of common knowledge. In many a laboratory extensive studies are un- derway of factors determining tumour tissue response to irradiation and of methods for exerting directional effect upon those factors. Such studies have revealed that, at least at the cellular level, a considerable number of factors manifest themselves which are respon- sible for radiation effect (1] - Among those are: spatial heteroge- neity of tumour cell population producing radioresistant cell reser- ves (hypoxic cells of solid tumours); differing radiosensitivities of cell life cycle phases; intrinsic dynamics of the processes of radi- ation damage and postradiation cell recovery; induction of prolifera- tive processes in response to the death of some cells within the po- pulation; the stochastic nature of cell kinetics and complicated in- teraction between individual cell subpopulations corresponding to di- fferent tumour loci. Questions arise as to whether the researchers are now in possession of adequate means for interpreting experimental findings and clinical evidence and whether there are procedures for performing complex analysis and predicting specific tumour responses to various irradiation regimens and to combined antitumoral effects, taking into account the complexities of the phenomena under study.
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Computer Simulation in Cell Radiobiology (Lecture Notes in Biomathematics, 74)
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Computer Simulation in Cell Radiobiology
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Computer Simulation in Cell Radiobiology (Paperback)
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Springer-Verlag Berlin and Heidelberg GmbH & Co. KG, Berlin, 1988
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Paperback. Etat : new. Paperback. The search for ways to overcome tumour radioresistance is a major problem of experimental and clinical radiation oncology. The diffi- culties involved in the attempts to solve this problem are a matter of common knowledge. In many a laboratory extensive studies are un- derway of factors determining tumour tissue response to irradiation and of methods for exerting directional effect upon those factors. Such studies have revealed that, at least at the cellular level, a considerable number of factors manifest themselves which are respon- sible for radiation effect (1] * Among those are: spatial heteroge- neity of tumour cell population producing radioresistant cell reser- ves (hypoxic cells of solid tumours); differing radiosensitivities of cell life cycle phases; intrinsic dynamics of the processes of radi- ation damage and postradiation cell recovery; induction of prolifera- tive processes in response to the death of some cells within the po- pulation; the stochastic nature of cell kinetics and complicated in- teraction between individual cell subpopulations corresponding to di- fferent tumour loci.Questions arise as to whether the researchers are now in possession of adequate means for interpreting experimental findings and clinical evidence and whether there are procedures for performing complex analysis and predicting specific tumour responses to various irradiation regimens and to combined antitumoral effects, taking into account the complexities of the phenomena under study. The search for ways to overcome tumour radioresistance is a major problem of experimental and clinical radiation oncology. The diffiA culties involved in the attempts to solve this problem are a matter of common knowledge. In many a laboratory extensive studies are unA derway of factors determining tumour tissue response to irradiation and of methods for exerting directional effect upon those factors. Such studies have revealed that, at least at the cellular level, a considerable number of factors manifest themselves which are responA sible for radiation effect (1] a Among those are: spatial heterogeA neity of tumour cell population producing radioresistant cell reserA ves (hypoxic cells of solid tumours); differing radiosensitivities of cell life cycle phases; intrinsic dynamics of the processes of radiA ation damage and postradiation cell recovery; induction of proliferaA tive processes in response to the death of some cells within the poA pulation; the stochastic nature of cell kinetics and complicated inA teraction between individual cell subpopulations corresponding to diA fferent tumour loci. Questions arise as to whether the researchers are now in possession of adequate means for interpreting experimental findings and clinical evidence and whether there are procedures for performing complex analysis and predicting specific tumour responses to various irradiation regimens and to combined antitumoral effects, taking into account the complexities of the phenomena Shipping may be from multiple locations in the US or from the UK, depending on stock availability. N° de réf. du vendeur 9783540194576
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Computer simulation in cell radiobiology. Lecture notes in biomathematics; 74.
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Computer Simulation in Cell Radiobiology (Lecture Notes in Biomathematics, 74)
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Computer Simulation in Cell Radiobiology (Lecture Notes in Biomathematics, 74)
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Computer Simulation in Cell Radiobiology
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Springer Berlin Heidelberg, J.B. Metzler Jun 1988, 1988
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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The search for ways to overcome tumour radioresistance is a major problem of experimental and clinical radiation oncology. The diffi culties involved in the attempts to solve this problem are a matter of common knowledge. In many a laboratory extensive studies are un derway of factors determining tumour tissue response to irradiation and of methods for exerting directional effect upon those factors. Such studies have revealed that, at least at the cellular level, a considerable number of factors manifest themselves which are respon sible for radiation effect (1] Among those are: spatial heteroge neity of tumour cell population producing radioresistant cell reser ves (hypoxic cells of solid tumours); differing radiosensitivities of cell life cycle phases; intrinsic dynamics of the processes of radi ation damage and postradiation cell recovery; induction of prolifera tive processes in response to the death of some cells within the po pulation; the stochastic nature of cell kinetics and complicated in teraction between individual cell subpopulations corresponding to di fferent tumour loci. Questions arise as to whether the researchers are now in possession of adequate means for interpreting experimental findings and clinical evidence and whether there are procedures for performing complex analysis and predicting specific tumour responses to various irradiation regimens and to combined antitumoral effects, taking into account the complexities of the phenomena under study. 140 pp. Englisch. N° de réf. du vendeur 9783540194576
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Computer Simulation in Cell Radiobiology
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Springer Berlin Heidelberg, 1988
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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Simulation in Cell Populations Kinetics.- A Simulation Model for In Vitro Kinetics of Normal and Irradiated Cells.- Simulation and Analysis Op Radiobiological Effects in Cell Cultures.- Simulation of Controlled Cell Systems.- The Properties of Cell Kinetics. N° de réf. du vendeur 4884171
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Computer Simulation in Cell Radiobiology (Lecture Notes in Biomathematics (closed))
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Paperback. Etat : Brand New. 1988 edition. 140 pages. 9.01x5.98x0.32 inches. In Stock. N° de réf. du vendeur x-3540194576
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Computer Simulation in Cell Radiobiology
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Springer Berlin Heidelberg, Springer Berlin Heidelberg Jun 1988, 1988
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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -The search for ways to overcome tumour radioresistance is a major problem of experimental and clinical radiation oncology. The diffi culties involved in the attempts to solve this problem are a matter of common knowledge. In many a laboratory extensive studies are un derway of factors determining tumour tissue response to irradiation and of methods for exerting directional effect upon those factors. Such studies have revealed that, at least at the cellular level, a considerable number of factors manifest themselves which are respon sible for radiation effect (1] ¿ Among those are: spatial heteroge neity of tumour cell population producing radioresistant cell reser ves (hypoxic cells of solid tumours); differing radiosensitivities of cell life cycle phases; intrinsic dynamics of the processes of radi ation damage and postradiation cell recovery; induction of prolifera tive processes in response to the death of some cells within the po pulation; the stochastic nature of cell kinetics and complicated in teraction between individual cell subpopulations corresponding to di fferent tumour loci. Questions arise as to whether the researchers are now in possession of adequate means for interpreting experimental findings and clinical evidence and whether there are procedures for performing complex analysis and predicting specific tumour responses to various irradiation regimens and to combined antitumoral effects, taking into account the complexities of the phenomena under study.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 140 pp. Englisch. N° de réf. du vendeur 9783540194576
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