Articles liés à Chemokine Roles in Immunoregulation and Disease

Chemokine Roles in Immunoregulation and Disease - Couverture rigide

 
9783540402213: Chemokine Roles in Immunoregulation and Disease
Couverture rigide
ISBN 10 : 3540402217 ISBN 13 : 9783540402213
Editeur : Springer-Verlag Berlin and Heidelberg GmbH & Co. K, 2003

Synopsis

In autumn 2002, the Ernst Schering Research Foundation Workshop sponsored the 45th in its series of conferences devoted to emerging areas in basic and applied biomedical research. These conferences bring together a critical mass of top scientists working in an impor tant area in an intimate setting that fosters the free exchange of knowledge and ideas. In this spirit, Workshop 45 assembled leaders in the field of chemokines - hemotactic cytokines that coordinate leukocyte trafficking - amid the scenic vineyards and wineries of Napa Valley, to discuss the latest concepts of how these molecules regulate the immune response and disease. Chemokines were se lected as a conference topic because they have revitalized the study of leukocyte trafficking and are widely considered to be potential new targets for drug development, in diseases ranging from acute in flammation and autoimmunity to HIV and cancer. Discovered in the 1980s, the chemokine superfamily currently has 43 human members, making it the largest subset of cytokines. Mem bers are defined by conserved sequences and a common three-di mensional fold, and can be divided into two major functional groups - homeostatic and inflammatory - depending on whether they are produced constitutively, and thereby control basal lymphocyte traf ficking, or whether they must be induced, for example by pathogens or injury, and thereby control deployment of effector leukocytes in emergencies."

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Éditeur
Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Date d'édition
2003
Langue
anglais
ISBN 10 
3540402217
ISBN 13 
9783540402213
Reliure
Relié
Nombre de pages
175
Éditeur
Murphy Philip M., Horuk Richard
Coordonnées du fabricant
non disponible
Personne responsable
CMN Printpool Inh. Mathis Neumann
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