Structure-Based Drug Design: Thermodynamics, Modeling and Strategy - Couverture rigide

Couverture rigide

ISBN 10 : 3540632506 ISBN 13 : 9783540632504

Editeur : Springer-Verlag Berlin and Heidelberg GmbH & Co. K, 1997

Synopsis

This is a discussion of the properties that follow from the principles of thermodynamics, aiming to bridge the gap in showing applications of model molecules in modern drug design. The book connects two subjects: drug design - a biological science - and thermodynamics - a physical science. Armed with the knowledge of the three-dimensional structure of a potential binding site of a molecule, the method of structure-based design provides a rapid, rational route to a ligand molecule. Recent developments in the determination of structure and the measurement of thermodynamic parameters of binding have resulted in drawing theoretical and experimental data together to improve ability to model these interactions afresh. The book also outlines future developments in the field of structure-based ligand design.

Détails de l'édition

• Éditeur: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
• Date d'édition: 1997
• Langue: anglais
• ISBN 10: 3540632506
• ISBN 13: 9783540632504
• Reliure: Relié
• Nombre de pages: 198
• Éditeur: Ladbury J.E., Connelly P.R.
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible