Failure of Apoptosis and Cancer Metastasis - Couverture rigide

Glinsky, G.V.

Couverture rigide

ISBN 10 : 3540645608 ISBN 13 : 9783540645603

Editeur : Springer-Verlag Berlin and Heidelberg GmbH & Co. K, 1998

Synopsis

This is a summary of reports on adhesion-dependent regulation of apoptosis. The author discusses data indicating that highly metastatic cancer cells exhibit a superior survival ability and resistance to apoptosis induce by diverse external signals. He also shows that increased survival of metastatic cancer cells compared to nonmetastatic or poorly metastatic cells is associated with their enhanced galectin-mediated homotypic aggregation and dysfunction of adhesion-dependent regulation of apoptosis. Profound deficiency of two major apoptosis execution mechanisms has been identified as a main characteristic of apoptosis failure in metastatic cancer cells.

Détails de l'édition

• Éditeur: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
• Date d'édition: 1998
• Langue: anglais
• ISBN 10: 3540645608
• ISBN 13: 9783540645603
• Reliure: Relié
• Nombre de pages: 195
• Coordonnées du fabricant: non disponible
• Personne responsable: CMN Printpool Inh. Mathis Neumann; https://www.also.com/ec/cms5/en_6000/6000/index.jsp; ; Friedrich-Karl-Str. 9; Hamburg; Allemagne