Sparking Signals: Kinases As Molecular Signaltransducers and Pharmacologial Drug Targets in Inflammation - Couverture rigide

 
9783540735007: Sparking Signals: Kinases As Molecular Signaltransducers and Pharmacologial Drug Targets in Inflammation
Couverture rigide
ISBN 10 : 3540735003 ISBN 13 : 9783540735007
Editeur : Springer-Verlag Berlin and Heidelberg GmbH & Co. K, 2008

Synopsis

Protein phosphorylation is an essential post-translational modification that modulates cell-cell communication. Substrate phosphorylation by protein kinases controls intracellular signal transduction pathways that mediate cell proliferation, migration, differentiation, and metabolism. The importance of the protein kinase family is underscored by numerous disease states that arise due to dysregulation of kinase activity. Recent progress in understanding the molecular regulation of kinases has led to the development of new therapeutics based on the inhibition of kinase activity. Inhibitors that target protein kinases have proven efficacious in clinical settings and their continued development is the current focus of many drug discovery groups.

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Éditeur
Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Date d'édition
2008
Langue
anglais
ISBN 10 
3540735003
ISBN 13 
9783540735007
Reliure
Relié
Nombre de pages
201
Éditeur
Baier Gottfried, Schraven Burkhart, Zügel Ulrich, Bonin Arne
Coordonnées du fabricant
ProductSafety@springernature.com
ProductSafety@springernature.com

Poststr. 9
Darmstadt
64293
Allemagne

Autres éditions populaires du même titre

9783642092626: Sparking Signals: Kinases as Molecular Signaltransducers and Pharmacological Drug Targets in Inflammation

Edition présentée

ISBN 10 :  3642092624 ISBN 13 :  9783642092626
Editeur : Springer, 2010
Couverture souple