In the field of bio-informatics, the analysis of voluminous data is becoming increasingly crucial to understanding the underlying biology and answering important questions. Clustering techniques often in combination with visualization techniques are extensively used, say, to find the functions of unknown genes through pattern detection and analysis. Similar to clustering of gene expression data is that of clustering the characteristics of protein folding dynamics. The mechanism of protein folding remains largely a mystery. Currently, protein folding dynamics is often characterized by calculating the free energy landscape versus various reaction coordinates such as the fraction of native contacts, the radius of gyration and so on. We present the development of a visual analytics tool, PROTERAN, which enables one to view the changing landscape of major protein fold states through the metaphor of animated terrains. PROTERAN promotes the use of an integrated approach towards understanding the folding process via interactive visual analysis of patterns of these reaction coordinates.
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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - In the field of bio-informatics, the analysis ofvoluminous data is becoming increasingly crucial tounderstanding the underlying biology and answeringimportant questions. Clustering techniques often incombination with visualization techniques areextensively used, say, to find the functions ofunknown genes through pattern detection and analysis.Similar to clustering of gene expression data isthat of clustering the characteristics of proteinfolding dynamics. The mechanism of protein foldingremains largely a mystery. Currently, proteinfolding dynamics is often characterized bycalculating the free energy landscape versus variousreaction coordinates such as the fraction of nativecontacts, the radius of gyration and so on. Wepresent the development of a visual analytics tool,PROTERAN, which enables one to view the changinglandscape of major protein fold states through themetaphor of animated terrains. PROTERAN promotes theuse of an integrated approach towards understandingthe folding process via interactive visual analysisof patterns of these reaction coordinates. N° de réf. du vendeur 9783639100402
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Taschenbuch. Etat : Neu. Visual Analytics for Protein Folding | PROTERAN: Analyzing Protein Folds Using Animated Terrains | Kush Kapila | Taschenbuch | Kartoniert / Broschiert | Englisch | 2008 | VDM Verlag Dr. Müller | EAN 9783639100402 | Verantwortliche Person für die EU: OmniScriptum GmbH & Co. KG, Bahnhofstr. 28, 66111 Saarbrücken, info[at]akademikerverlag[dot]de | Anbieter: preigu. N° de réf. du vendeur 101689727
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