Data Analysis for Mass Spectrometry-Based Proteomics: Novel Data Analysis Methods and Algorithms for Identification of Peptides and Proteins by Use of Tandem Mass Spectrometry - Couverture souple

Xu, Hua

 
9783639105254: Data Analysis for Mass Spectrometry-Based Proteomics: Novel Data Analysis Methods and Algorithms for Identification of Peptides and Proteins by Use of Tandem Mass Spectrometry
Couverture souple
ISBN 10 : 3639105257 ISBN 13 : 9783639105254
Editeur : VDM Verlag Dr. Müller, 2008

Synopsis

Tandem mass spectrometry is one of the most important tools for protein analysis. This work is focused on the development of new methods and algorithms for tandem mass spectrometry data analysis. A database search engine, MassMatrix, has also been developed that incorporates these methods and algorithms. The program is publicly available both on the web server at www.massmatrix.net and as a deliverable software package for personal computers. Three different scoring algorithms have been developed to identify and characterize proteins and peptides by use of tandem mass spectrometry data. In addition, a data analysis method for identification of disulfide bonds in proteins and peptides by tandem mass spectrometry data has been developed and incorporated in MassMatrix. By this new approach, proteins and peptides with disulfide bonds can be directly identified in tandem mass spectrometry with high confidence without any chemical reduction and/or other derivatization.

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Présentation de l'éditeur

Tandem mass spectrometry is one of the most important tools for protein analysis. This work is focused on the development of new methods and algorithms for tandem mass spectrometry data analysis. A database search engine, MassMatrix, has also been developed that incorporates these methods and algorithms. The program is publicly available both on the web server at www.massmatrix.net and as a deliverable software package for personal computers. Three different scoring algorithms have been developed to identify and characterize proteins and peptides by use of tandem mass spectrometry data. In addition, a data analysis method for identification of disulfide bonds in proteins and peptides by tandem mass spectrometry data has been developed and incorporated in MassMatrix. By this new approach, proteins and peptides with disulfide bonds can be directly identified in tandem mass spectrometry with high confidence without any chemical reduction and/or other derivatization.

Biographie de l'auteur

Hua Xu, Ph.D.: Studied Bioinformatics and Mass Spectrometry-Based Proteomics at The Ohio State University. Research Specialist at University of Illinois at Chicago.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
VDM Verlag Dr. Müller
Date d'édition
2008
Langue
anglais
ISBN 10 
3639105257
ISBN 13 
9783639105254
Reliure
Broché
Nombre de pages
236
Coordonnées du fabricant
non disponible
Personne responsable
non disponible