The advent of low-cost mass-sequencing of genomes presents significant data management difficulties. These will grow worse as it becomes routine to sequence the genomes of individual people and organisms, because existing systems store and search each genome separately. This approach is not feasible for searching and comparing the genomes of millions or billions of individual organisms. This book seeks to solve this problem by describing the DASH sequence alignment and compression algorithms. DASH makes use of the overwhelming similarities amongst genomes of a given species in order to compress, not only the database size, but also the index size and search time. The resulting novel approach to database compression, index compression, bioinformatics and information-retrieval should be of especial interest to anyone who has an interest in the storage and efficient searching of large data sets, whether DNA or any other subject which offers some degree of redundancy, such as natural language text or web pages.
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Dr. Paul Gardner-Stephen, BSc, PhD: Studied computer science (BSc) and bioinformatics (PhD) at Flinders University, Adelaide, Australia. Post doctoral fellow in bioinformatics and systems and network administrator at Flinders University, Adelaide, Australia.
Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.
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Kartoniert / Broschiert. Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Gardner-Stephen PaulDr. Paul Gardner-Stephen, BSc, PhD: Studied computer sciencen(BSc) and bioinformatics (PhD) at Flinders University, Adelaide,nAustralia. Post doctoral fellow in bioinformatics and systemsnand network administrato. N° de réf. du vendeur 4959355
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Taschenbuch. Etat : Neu. DASH: Searching Compressed DNA | Creating and Searching Compact Databases for The Genomic Era | Paul Gardner-Stephen | Taschenbuch | Englisch | VDM Verlag Dr. Müller | EAN 9783639121292 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. N° de réf. du vendeur 101659654
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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The advent of low-cost mass-sequencing of genomespresents significant data management difficulties.These will grow worse as it becomes routine tosequence the genomes of individual people andorganisms, because existing systems store and searcheach genome separately. This approach is notfeasible for searching andcomparing the genomes of millions or billions ofindividual organisms. This book seeks to solve thisproblem by describing the DASH sequence alignment andcompression algorithms. DASHmakes use of the overwhelming similarities amongstgenomes of a given species in order to compress, notonly the database size, but also the index size andsearch time. The resulting novel approach todatabase compression, index compression,bioinformatics and information-retrieval should be ofespecial interest to anyone who has an interest inthe storage and efficient searching of large datasets, whether DNA or any other subject which offerssome degree of redundancy, such as natural languagetext or web pages. N° de réf. du vendeur 9783639121292
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