Microfluidic Technologies for Single-Cell Analysis: Creating uniform cellular microenvironments for fast timescale measurements - Couverture souple

Di Carlo, Dino

 
9783639139518: Microfluidic Technologies for Single-Cell Analysis: Creating uniform cellular microenvironments for fast timescale measurements
Couverture souple
ISBN 10 : 3639139518 ISBN 13 : 9783639139518
Editeur : VDM Verlag, 2009

Synopsis

Analysis of single cells allows a complete understanding of the heterogeneity that is present in cell behavior and function. Current single-cell analysis methods provide high-throughput information about labeled biomolecules within cells, but often cannot follow the dynamic processes occurring in signaling pathways. New microfluidic methods have separately allowed assays of fast timescale responses or creation of uniform environments to study cell behavior in a more quantitative manner. This book focuses on microfluidic hydrodynamic trapping techniques that aid in both fast timescale measurements and uniform environmental control in a single platform. Example applications for fast timescale analysis of pore-forming toxin insertion into membranes and assays of single-cell enzyme content will be presented. The book would be of interest to analytical chemists, engineers, and biologists developing platforms to study single-cell behavior. Also, biologists looking for tools to study cells of interest with statistical accuracy would find the book most helpful.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Analysis of single cells allows a complete understanding of the heterogeneity that is present in cell behavior and function. Current single-cell analysis methods provide high-throughput information about labeled biomolecules within cells, but often cannot follow the dynamic processes occurring in signaling pathways. New microfluidic methods have separately allowed assays of fast timescale responses or creation of uniform environments to study cell behavior in a more quantitative manner. This book focuses on microfluidic hydrodynamic trapping techniques that aid in both fast timescale measurements and uniform environmental control in a single platform. Example applications for fast timescale analysis of pore-forming toxin insertion into membranes and assays of single-cell enzyme content will be presented. The book would be of interest to analytical chemists, engineers, and biologists developing platforms to study single-cell behavior. Also, biologists looking for tools to study cells of interest with statistical accuracy would find the book most helpful.

Biographie de l'auteur

Dino Di Carlo is an Assistant Professor of Bioengineering at UCLA. He received his B.S. and Ph.D. in Bioengineering from UC Berkeley and San Francisco. He then conducted postdoctoral studies at Harvard Medical School and MGH. His research focuses on miniaturization technologies for advanced diagnostic and automated single cell analysis systems.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
VDM Verlag
Date d'édition
2009
Langue
anglais
ISBN 10 
3639139518
ISBN 13 
9783639139518
Reliure
Broché
Nombre de pages
116
Coordonnées du fabricant
non disponible
Personne responsable
non disponible