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How a Molecule Folds: Techniques of Simulating Protein and RNA Molecular Motions - Couverture souple

Tang, Xinyu

 
9783639227161: How a Molecule Folds: Techniques of Simulating Protein and RNA Molecular Motions
Couverture souple
ISBN 10 : 3639227166 ISBN 13 : 9783639227161
Editeur : VDM Verlag Dr. Müller, 2010

Synopsis

This book introduces a novel framework that can be applied to study a range of molecular motions. Currently, we use it to study the protein and RNA folding process which is critical for their functions. This folding process is difficult to observe experimentally, therefore, computational methods such as simulation are very important and useful in the study of such process. The key advantage of the method introduced in this book over other computational techniques is that this approach is fast and efficient while bridging the gap between high-level folding events and low-level folding details. This advantage is validated by comparison with other computational methods and that with with experimental studies of RNA and protein. This book includes two experimental cases that clearly show how we can predict kinetics-based functional rates of ColE1 RNAII and MS2 phage RNA and their mutants using our simulation techniques. The target audience for the book is primarily researchers and students in bioinformatics, but researchers and students in other fields of computer science and molecular biology should also find this useful.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

This book introduces a novel framework that can be applied to study a range of molecular motions. Currently, we use it to study the protein and RNA folding process which is critical for their functions. This folding process is difficult to observe experimentally, therefore, computational methods such as simulation are very important and useful in the study of such process. The key advantage of the method introduced in this book over other computational techniques is that this approach is fast and efficient while bridging the gap between high-level folding events and low-level folding details. This advantage is validated by comparison with other computational methods and that with with experimental studies of RNA and protein. This book includes two experimental cases that clearly show how we can predict kinetics-based functional rates of ColE1 RNAII and MS2 phage RNA and their mutants using our simulation techniques. The target audience for the book is primarily researchers and students in bioinformatics, but researchers and students in other fields of computer science and molecular biology should also find this useful.

Biographie de l'auteur

Xinyu Tang earned his Ph.D. in Computer Science from Texas A&M University and is a software engineer in Google Inc.. He also obtained his M.S. and B.S. in Computer Science. His research interests include algorithms, bioinformatics, robotics, computer graphics and animation.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
VDM Verlag Dr. Müller
Date d'édition
2010
Langue
anglais
ISBN 10 
3639227166
ISBN 13 
9783639227161
Reliure
Broché
Nombre de pages
100
Coordonnées du fabricant
non disponible
Personne responsable
non disponible