Articles liés à Transport Phenomena in Intervertebral Disc: Modeling...

Transport Phenomena in Intervertebral Disc: Modeling Molecular Transport and Binding Interactions in the Extracellular Matrix of the Intervertebral Disc - Couverture souple

Travascio, Francesco

 
9783639245042: Transport Phenomena in Intervertebral Disc: Modeling Molecular Transport and Binding Interactions in the Extracellular Matrix of the Intervertebral Disc
Couverture souple
ISBN 10 : 3639245040 ISBN 13 : 9783639245042
Editeur : VDM Verlag Dr. Müller, 2010

Synopsis

Low back pain represents a significant concern in the United States, with 70% of individuals experiencing symptoms at some point in their lifetime. Symptoms of low back pain have been strongly associated with degeneration of the intervertebral disc. Insufficient nutritional supply is believed to be a major mechanism for disc degeneration. Thus, understanding nutrients' transport in intervertebral disc is crucial to elucidate the etiology of disc degeneration, and to develop strategies for tissue repair, and tissue engineering. Transport phenomena in intervertebral disc are still poorly understood. This is partly due to the limited number of available experimental techniques for investigating transport properties, and the paucity of theoretical or numerical methods for predicting solute transport in the disc. In this work, new fluorescence imaging techniques were developed to experimentally determine solute transport properties in intervertebral disc. In addition, a mixture theory for charged hydrated soft tissues was presented as a theoretical framework for investigating on molecular transport and binding interactions in the disc.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Low back pain represents a significant concern in the United States, with 70% of individuals experiencing symptoms at some point in their lifetime. Symptoms of low back pain have been strongly associated with degeneration of the intervertebral disc. Insufficient nutritional supply is believed to be a major mechanism for disc degeneration. Thus, understanding nutrients' transport in intervertebral disc is crucial to elucidate the etiology of disc degeneration, and to develop strategies for tissue repair, and tissue engineering. Transport phenomena in intervertebral disc are still poorly understood. This is partly due to the limited number of available experimental techniques for investigating transport properties, and the paucity of theoretical or numerical methods for predicting solute transport in the disc. In this work, new fluorescence imaging techniques were developed to experimentally determine solute transport properties in intervertebral disc. In addition, a mixture theory for charged hydrated soft tissues was presented as a theoretical framework for investigating on molecular transport and binding interactions in the disc.

Biographie de l'auteur

Francesco Travascio, Ph.D., graduated in Biomedical Engineering at the University of Miami. His research activity focuses on low back pain and the etiology of intervertebral disc degeneration. He is currently working as Post Doctoral Associate at the Tissue Biomechanics Laboratory of the University of Miami.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
VDM Verlag Dr. Müller
Date d'édition
2010
Langue
anglais
ISBN 10 
3639245040
ISBN 13 
9783639245042
Reliure
Broché
Nombre de pages
216
Coordonnées du fabricant
non disponible
Personne responsable
non disponible