Dermo-follicular Proliferation: A Scientific Study - Couverture souple

Tripathi, Atul; Neeraj Upmanyu, Dr.; N. Ganesh, Dr.

 
9783639324006: Dermo-follicular Proliferation: A Scientific Study
Couverture souple
ISBN 10 : 3639324005 ISBN 13 : 9783639324006
Editeur : VDM Verlag Dr. Müller, 2011

Synopsis

Alopecia was induced in mice by administration of Paclitaxel. As we know that chemotherapy signatured for miniaturization of hair follicle and changes the proliferation rate of hair growth by inhibiting growth cycle, which further leads to hair falling and defined as alopecia. To recover and compensate alopetic condition the drug of choice available i.e. Minoxidil, a vasodilator medication which slow and steady stop the hair falling or also have potential to proliferate hair follicles by widening blood vessels and opening potassium channels, it allows more oxygen, blood and nutrients to the follicle. This can also cause follicles in the telogen phase to shed, usually soon to be replaced by new, thicker hairs (in a new anagen phase). The alopecia, induced in the mice by Paclitaxel, was counteracted when solvent Ethanol:PEG:Water was administered simultaneously to the mice. The alopecia was not observed in groups that were treated with crude extract or Minoxidil along with Paclitaxel. Besides visual observation, quantitative data (e.g., A/T ratio and follicular density) also suggest inhibition of alopetic activity of the drug.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Alopecia was induced in mice by administration of Paclitaxel. As we know that chemotherapy signatured for miniaturization of hair follicle and changes the proliferation rate of hair growth by inhibiting growth cycle, which further leads to hair falling and defined as alopecia. To recover and compensate alopetic condition the drug of choice available i.e. Minoxidil, a vasodilator medication which slow and steady stop the hair falling or also have potential to proliferate hair follicles by widening blood vessels and opening potassium channels, it allows more oxygen, blood and nutrients to the follicle. This can also cause follicles in the telogen phase to shed, usually soon to be replaced by new, thicker hairs (in a new anagen phase). The alopecia, induced in the mice by Paclitaxel, was counteracted when solvent Ethanol:PEG:Water was administered simultaneously to the mice. The alopecia was not observed in groups that were treated with crude extract or Minoxidil along with Paclitaxel. Besides visual observation, quantitative data (e.g., A/T ratio and follicular density) also suggest inhibition of alopetic activity of the drug.

Biographie de l'auteur

Atul Tripathi received his M. Pharm (Pharmacology) from Rajiv Gandhi Prodougiki Vishwavidhyalaya, Bhopal, India. He is working on hair growth promoters of herbal origin.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
VDM Verlag Dr. Müller
Date d'édition
2011
Langue
anglais
ISBN 10 
3639324005
ISBN 13 
9783639324006
Reliure
Broché
Nombre de pages
160
Coordonnées du fabricant
non disponible
Personne responsable
non disponible