REPIMELTS AND ITS SPECIAL PERSPECTIVES: formulations and its developments - Couverture souple

Vishwakarma, Pushpendra Kumar; Patidar, Abhishek; Singh Lodhi, Narendra

Couverture souple

ISBN 10 : 3639355652 ISBN 13 : 9783639355659

Editeur : VDM Verlag Dr. Müller, 2011

Synopsis

Tablet is the most popular among all dosage forms existing today because of its convenience of self administration, compactness and easy manufacturing; however hand tremors, dysphasia in case of geriatric patients, the underdeveloped muscular and nervous systems in young individuals and h case of uncooperative patients, the problem of swallowing is common phenomenon which leads to poor patient compliance To overcome these drawbacks, mouth dissolving tablets (MDT) or orally disintegrating tablets; (ODT) has emerged as alternative oral dosage forms. These are novel types; of tablets that disintegrate/dissolve/ disperse in saliva within few seconds'. According to European Pharmacopoeia, the ODT should disperse/disintegrate in less than three minutes. The basic approach used in development of MDT is the use of superdisintegrants like Cross linked carboxymelhylcellulose (Croscarmeliose), Sodium starch glycol ate (Primogel, Explotab). Polyvinylpyrrolidone (Polyplasdone) etc. which provide instantaneous disintegration of tablet after putting on tongue, thereby releasing the drug in saliva.

Détails de l'édition

• Éditeur: VDM Verlag Dr. Müller
• Date d'édition: 2011
• Langue: anglais
• ISBN 10: 3639355652
• ISBN 13: 9783639355659
• Reliure: Broché
• Nombre de pages: 136
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible