Application of the Difference Map Algorithm: to Protein Structure Prediction - Couverture souple

Rankenburg, Ivan

 
9783639440621: Application of the Difference Map Algorithm: to Protein Structure Prediction
Couverture souple
ISBN 10 : 3639440625 ISBN 13 : 9783639440621
Editeur : AV Akademikerverlag, 2012

Synopsis

Revision with unchanged content. A powerful new search algorithm, the difference map, has had notable success in many fields that involve finding a characteristic point in a high dimensional search space. The algorithm was first applied to a toy model of proteins in 2004. In that context, the difference map was able to find low energy "folds" better than any contemporary search algorithm. In this work, the same algorithm is applied to a realistic protein model. Though the algorithm finds low energy folds for the protein molecule, the energy function used is found to be inadequate to make the lowest energy state of the protein molecule the native conformation. In this work, the algorithm is described, and some example applications are given. Finally, the complete programming implementation of the algorithm to the problem of protein energy minimization is supplied.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Revision with unchanged content. A powerful new search algorithm, the difference map, has had notable success in many fields that involve finding a characteristic point in a high dimensional search space. The algorithm was first applied to a toy model of proteins in 2004. In that context, the difference map was able to find low energy "folds" better than any contemporary search algorithm. In this work, the same algorithm is applied to a realistic protein model. Though the algorithm finds low energy folds for the protein molecule, the energy function used is found to be inadequate to make the lowest energy state of the protein molecule the native conformation. In this work, the algorithm is described, and some example applications are given. Finally, the complete programming implementation of the algorithm to the problem of protein energy minimization is supplied.

Biographie de l'auteur

The author received his B.S. in math and physics from U.C. Davis in 2001, and his PhD in physics from Cornell in 2007. During his studies, he has done experiments on sphere packing in two dimensions, turbulence measurements, computer simulations of superfluid helium vortex's, the subset sum problem, and finally protein structure prediction.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
AV Akademikerverlag
Date d'édition
2012
Langue
anglais
ISBN 10 
3639440625
ISBN 13 
9783639440621
Reliure
Broché
Nombre de pages
208
Coordonnées du fabricant
non disponible
Personne responsable
non disponible

Autres éditions populaires du même titre

9783836471060: Application of the Difference Map Algorithm to Protein Structure Prediction

Edition présentée

ISBN 10 :  383647106X ISBN 13 :  9783836471060
Editeur : VDM Verlag Dr. Mueller E.K., 2008
Couverture souple