Cefixime Trihydrate Sustained Release Matrix Tablet: To study the effect of different viscosity grade of HPMC on Cefixime Trihydrate sustained Release Matrix Tablet - Couverture souple
Synopsis
The present work aims to study effect of diff. viscosity grade of HPMC on cefixime trihydrate sustained release matrix tablet with a view to prolong drug release in vivo & reduce frequency of dosing. Cefixime Trihydrate is an orally active third generation cephalosporin and active against Gram+ve as well as Gram -ve bacteria. It has plasma half-life of 3-4 hrs. The Sustained release matrix tablets were prepared by wet granulation method using diff. grade of HPMC, Lactose, MCC & PVP K-30. The granules were subjected to pre-compression & post-compression parameters and they were in the acceptable limits. The in vitro drug release from HPMC matrices in accordance with its diff. proportion and viscosity grade was HPMC K-100M > K-15M > K-4M with ratio of (1, 1.5, 2) individually in formulation F1-F9 and (0.5, 0.75, 1) ratio in F10-F12. Drug-excipient interaction was performed by DSC & FTIR; results were shown that there was no interaction. After 3 months stability study at 400C/75% RH, formulations found to be stable. So as the viscosity and proportion of HPMC increases release rate from sustained release cefixime trihydrate matrix tablet decreases.
Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.
À propos de l'auteur
Parth B. Patel, Masters In Pharmacy (Pharmaceutics)Kalol Institute of Pharmacy, Gujarat Technological University, Gujarat
Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.
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Cefixime Trihydrate Sustained Release Matrix Tablet
Edité par
Scholars' Press Jul 2013, 2013
ISBN 10 : 3639515536
ISBN 13 : 9783639515534
Neuf
Taschenbuch
Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne
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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The present work aims to study effect of diff. viscosity grade of HPMC on cefixime trihydrate sustained release matrix tablet with a view to prolong drug release in vivo & reduce frequency of dosing. Cefixime Trihydrate is an orally active third generation cephalosporin and active against Gram+ve as well as Gram -ve bacteria. It has plasma half-life of 3-4 hrs. The Sustained release matrix tablets were prepared by wet granulation method using diff. grade of HPMC, Lactose, MCC & PVP K-30. The granules were subjected to pre-compression & post-compression parameters and they were in the acceptable limits. The in vitro drug release from HPMC matrices in accordance with its diff. proportion and viscosity grade was HPMC K-100M K-15M K-4M with ratio of (1, 1.5, 2) individually in formulation F1-F9 and (0.5, 0.75, 1) ratio in F10-F12. Drug-excipient interaction was performed by DSC & FTIR; results were shown that there was no interaction. After 3 months stability study at 400C/75% RH, formulations found to be stable. So as the viscosity and proportion of HPMC increases release rate from sustained release cefixime trihydrate matrix tablet decreases. 112 pp. Englisch. N° de réf. du vendeur 9783639515534
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Cefixime Trihydrate Sustained Release Matrix Tablet: To study the effect of different viscosity grade of HPMC on Cefixime Trihydrate sustained Release Matrix Tablet
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Cefixime Trihydrate Sustained Release Matrix Tablet
Edité par
Scholars\' Press, 2013
ISBN 10 : 3639515536
ISBN 13 : 9783639515534
Neuf
Couverture souple
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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Patel ParthParth B. Patel, Masters In Pharmacy (Pharmaceutics)Kalol Institute of Pharmacy, Gujarat Technological University, GujaratThe present work aims to study effect of diff. viscosity grade of HPMC on cefixime trihydrate sus. N° de réf. du vendeur 4993222
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Cefixime Trihydrate Sustained Release Matrix Tablet: To study the effect of different viscosity grade of HPMC on Cefixime Trihydrate sustained Release Matrix Tablet
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Etat : New. Print on Demand pp. 112. N° de réf. du vendeur 369821993
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Cefixime Trihydrate Sustained Release Matrix Tablet: To study the effect of different viscosity grade of HPMC on Cefixime Trihydrate sustained Release Matrix Tablet
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Cefixime Trihydrate Sustained Release Matrix Tablet
Edité par
Scholars' Press Jul 2013, 2013
ISBN 10 : 3639515536
ISBN 13 : 9783639515534
Neuf
Taschenbuch
Vendeur : buchversandmimpf2000, Emtmannsberg, BAYE, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -The present work aims to study effect of diff. viscosity grade of HPMC on cefixime trihydrate sustained release matrix tablet with a view to prolong drug release in vivo & reduce frequency of dosing. Cefixime Trihydrate is an orally active third generation cephalosporin and active against Gram+ve as well as Gram -ve bacteria. It has plasma half-life of 3-4 hrs. The Sustained release matrix tablets were prepared by wet granulation method using diff. grade of HPMC, Lactose, MCC & PVP K-30. The granules were subjected to pre-compression & post-compression parameters and they were in the acceptable limits. The in vitro drug release from HPMC matrices in accordance with its diff. proportion and viscosity grade was HPMC K-100M > K-15M > K-4M with ratio of (1, 1.5, 2) individually in formulation F1-F9 and (0.5, 0.75, 1) ratio in F10-F12. Drug-excipient interaction was performed by DSC & FTIR; results were shown that there was no interaction. After 3 months stability study at 400C/75% RH, formulations found to be stable. So as the viscosity and proportion of HPMC increases release rate from sustained release cefixime trihydrate matrix tablet decreases.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 112 pp. Englisch. N° de réf. du vendeur 9783639515534
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Cefixime Trihydrate Sustained Release Matrix Tablet : To study the effect of different viscosity grade of HPMC on Cefixime Trihydrate sustained Release Matrix Tablet
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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The present work aims to study effect of diff. viscosity grade of HPMC on cefixime trihydrate sustained release matrix tablet with a view to prolong drug release in vivo & reduce frequency of dosing. Cefixime Trihydrate is an orally active third generation cephalosporin and active against Gram+ve as well as Gram -ve bacteria. It has plasma half-life of 3-4 hrs. The Sustained release matrix tablets were prepared by wet granulation method using diff. grade of HPMC, Lactose, MCC & PVP K-30. The granules were subjected to pre-compression & post-compression parameters and they were in the acceptable limits. The in vitro drug release from HPMC matrices in accordance with its diff. proportion and viscosity grade was HPMC K-100M K-15M K-4M with ratio of (1, 1.5, 2) individually in formulation F1-F9 and (0.5, 0.75, 1) ratio in F10-F12. Drug-excipient interaction was performed by DSC & FTIR; results were shown that there was no interaction. After 3 months stability study at 400C/75% RH, formulations found to be stable. So as the viscosity and proportion of HPMC increases release rate from sustained release cefixime trihydrate matrix tablet decreases. N° de réf. du vendeur 9783639515534
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Cefixime Trihydrate Sustained Release Matrix Tablet | To study the effect of different viscosity grade of HPMC on Cefixime Trihydrate sustained Release Matrix Tablet
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Taschenbuch. Etat : Neu. Cefixime Trihydrate Sustained Release Matrix Tablet | To study the effect of different viscosity grade of HPMC on Cefixime Trihydrate sustained Release Matrix Tablet | Parth Patel (u. a.) | Taschenbuch | 112 S. | Englisch | 2013 | Scholars' Press | EAN 9783639515534 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. N° de réf. du vendeur 105612618
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Cefixime Trihydrate Sustained Release Matrix Tablet : To study the effect of different viscosity grade of HPMC on Cefixime Trihydrate sustained Release Matrix Tablet
Edité par
Scholars' Press, 2013
ISBN 10 : 3639515536
ISBN 13 : 9783639515534
Ancien ou d'occasion
Couverture souple
Vendeur : Buchpark, Trebbin, Allemagne
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Etat : Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | The present work aims to study effect of diff. viscosity grade of HPMC on cefixime trihydrate sustained release matrix tablet with a view to prolong drug release in vivo & reduce frequency of dosing. Cefixime Trihydrate is an orally active third generation cephalosporin and active against Gram+ve as well as Gram -ve bacteria. It has plasma half-life of 3-4 hrs. The Sustained release matrix tablets were prepared by wet granulation method using diff. grade of HPMC, Lactose, MCC & PVP K-30. The granules were subjected to pre-compression & post-compression parameters and they were in the acceptable limits. The in vitro drug release from HPMC matrices in accordance with its diff. proportion and viscosity grade was HPMC K-100M > K-15M > K-4M with ratio of (1, 1.5, 2) individually in formulation F1-F9 and (0.5, 0.75, 1) ratio in F10-F12. Drug-excipient interaction was performed by DSC & FTIR; results were shown that there was no interaction. After 3 months stability study at 400C/75% RH, formulations found to be stable. So as the viscosity and proportion of HPMC increases release rate from sustained release cefixime trihydrate matrix tablet decreases. N° de réf. du vendeur 24260589/2
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Cefixime Trihydrate Sustained Release Matrix Tablet: To study the effect of different viscosity grade of HPMC on Cefixime Trihydrate sustained Release Matrix Tablet
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